نتایج جستجو برای: hydrogels

تعداد نتایج: 10505  

2017
Fazli Wahid Cheng Zhong Hai-Song Wang Xiao-Hui Hu Li-Qiang Chu

Recently, the rapid emergence of antibiotic-resistant pathogens has caused a serious health problem. Scientists respond to the threat by developing new antimicrobial materials to prevent or control infections caused by these pathogens. Polymer-based nanocomposite hydrogels are versatile materials as an alternative to conventional antimicrobial agents. Cross-linking of polymeric materials by met...

2013
Min Zhu Yufang Zhu Lingxia Zhang Jianlin Shi

We have developed composite hydrogels of chitosan (CS) and mesoporous silica nanoparticles (MSNs) in this study. The gelation rate, gel strength, drug delivery behavior and chondrocyte proliferation properties were investigated. The introduction of MSNs into CS accelerated the gelation process at body temperature and also increased the elastic modulus G' from 1000 to 1800 Pa. When we used genta...

Journal: :Biotechnology and bioengineering 2014
Akhilesh K Gaharwar Nicholas A Peppas Ali Khademhosseini

Hydrogels mimic native tissue microenvironment due to their porous and hydrated molecular structure. An emerging approach to reinforce polymeric hydrogels and to include multiple functionalities focuses on incorporating nanoparticles within the hydrogel network. A wide range of nanoparticles, such as carbon-based, polymeric, ceramic, and metallic nanomaterials can be integrated within the hydro...

Journal: :Biofabrication 2011
Guo You Huang Li Hong Zhou Qian Cheng Zhang Yong Mei Chen Wei Sun Feng Xu Tian Jian Lu

With advanced properties similar to the native extracellular matrix, hydrogels have found widespread applications in tissue engineering. Hydrogel-based cellular constructs have been successfully developed to engineer different tissues such as skin, cartilage and bladder. Whilst significant advances have been made, it is still challenging to fabricate large and complex functional tissues due mai...

Journal: :Journal of biomedical materials research. Part A 2013
Joana Silva-Correia Antonio Gloria Mariana B Oliveira João F Mano Joaquim M Oliveira Luigi Ambrosio Rui L Reis

Tissue engineered hydrogels hold great potential as nucleus pulposus substitutes (NP), as they promote intervertebral disc (IVD) regeneration and re-establish its original function. But, the key to their success in future clinical applications greatly depends on its ability to replicate the native 3D micro-environment and circumvent their limitation in terms of mechanical performance. In the pr...

Journal: :Biomaterials science 2014
Chaenyung Cha Pranav Soman Wei Zhu Mehdi Nikkhah Gulden Camci-Unal Shaochen Chen Ali Khademhosseini

Hydrogels commonly used in tissue engineering are mechanically soft, thus often display structural weakness. Herein, we introduce a strategy for enhancing the structural integrity and fracture toughness of cell-laden hydrogels by incorporating a three-dimensional (3D) microfabricated scaffold as a structural element. A digital micromirror device projection printing (DMD-PP) system, a rapid prot...

2016
Hao Chen Shengzhen Hou Haili Ma Xu Li Yebang Tan

Gelation kinetics of hydrogels is closely linked to many applications such as the development of injectable and printable hydrogels. However, the control of gelation kinetics without compromising the structure and other properties of the hydrogels, remains a challenge. Here, we demonstrate a method to control the gelation kinetics of cucurbit[7]uril-adamantane (CB[7]-AD) cross-linked supramolec...

Journal: :Acta biomaterialia 2011
Ana C Borges Christian Eyholzer Fabien Duc Pierre-Etienne Bourban Philippe Tingaut Tanja Zimmermann Dominique P Pioletti Jan-Anders E Månson

The swelling and compressive mechanical behavior as well as the morphology and biocompatibility of composite hydrogels based on Tween® 20 trimethacrylate (T3), N-vinyl-2-pyrrolidone (NVP) and nanofibrillated cellulose (NFC) were assessed in the present study. The chemical structure of T3 was verified by Fourier transform infrared spectroscopy and proton nuclear magnetic resonance, and the degre...

Journal: :Tissue engineering. Part C, Methods 2014
Marina Matyash Florian Despang Chrysanthy Ikonomidou Michael Gelinsky

Soft alginate hydrogels support robust neurite outgrowth, but their rapid disintegration in solutions of high ionic strength restricts them from long-term in vivo applications. Aiming to enhance the mechanical stability of soft alginate hydrogels, we investigated how changes in pH and ionic strength during gelation influence the swelling, stiffness, and disintegration of a three-dimensional (3D...

2017
Qinyuan Chai Yang Jiao Xinjun Yu

Hydrogels are hydrophilic, three-dimensional networks that are able to absorb large quantities of water or biological fluids, and thus have the potential to be used as prime candidates for biosensors, drug delivery vectors, and carriers or matrices for cells in tissue engineering. In this critical review article, advantages of the hydrogels that overcome the limitations from other types of biom...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید