نتایج جستجو برای: hydrazone

تعداد نتایج: 2025  

Journal: :Monatshefte f�r Chemie 1920

Journal: :The Journal of pharmacology and experimental therapeutics 2013
Duo Lu Kurt Giles Zhe Li Satish Rao Elena Dolghih Joel R Gever Michal Geva Manuel L Elepano Abby Oehler Clifford Bryant Adam R Renslo Matthew P Jacobson Stephen J Dearmond B Michael Silber Stanley B Prusiner

The only small-molecule compound demonstrated to substantially extend survival in prion-infected mice is a biaryl hydrazone termed "Compd B" (4-pyridinecarboxaldehyde,2-[4-(5-oxazolyl)phenyl]hydrazone). However, the hydrazone moiety of Compd B results in toxic metabolites, making it a poor candidate for further drug development. We developed a pharmacophore model based on diverse antiprion comp...

Journal: :Journal of bacteriology 1980
E A Goulbourne E P Greenberg

The effects of various metabolic inhibitors on the motility of Spirochaeta aurantia were investigated. After 15 min in sodium arsenate buffer, 90% of cells remained motile even though adenosine triphosphate levels dropped from 5.6 to 0.1 nmol/mg (dry weight) of cells. After 70 min in sodium arsenate, 5% of cells were motile. Addition of phenazine methosulfate plus ascorbate at this time resulte...

Journal: :The Journal of biological chemistry 2008
Hideomi Itoh Tetsuya Suzuta Takayuki Hoshino Naoki Takaya

Hydrazines and their derivatives are versatile artificial and natural compounds that are metabolized by elusive biological systems. Here we identified microorganisms that assimilate hydrazones and isolated the yeast, Candida palmioleophila MK883. When cultured with adipic acid bis(ethylidene hydrazide) as the sole source of carbon, C. palmioleophila MK883 degraded hydrazones and accumulated adi...

Journal: :The Journal of organic chemistry 2010
Thomas C Pijper Dirk Pijper Michael M Pollard Frédéric Dumur Stephen G Davey Auke Meetsma Ben L Feringa

Controlling the unidirectional rotary process of second-generation molecular motors demands access to these motors in their enantiomerically pure form. In this paper, we describe an enantioselective route to three new second-generation light-driven molecular motors. Their synthesis starts with the preparation of an optically active alpha-methoxy-substituted upper-half ketone involving an enzyma...

Journal: :Chemical communications 2006
Subrata K Dey Laurence K Thompson Louise N Dawe

A compartmentalized {4 x[2 x 2]} Mn(II)16 antiferromagnetically coupled square grid results from the self-assembly reaction of a tetratopic pyridazine bis(hydrazone) ligand and Mn(II).

Journal: :Chemical communications 2012
Shufang Xue Lang Zhao Yun-Nan Guo Peng Zhang Jinkui Tang

A novel lanthanide molecular cluster pair (MCP), displaying single molecule magnet behaviour, was assembled using the novel o-vanilloyl hydrazone ligand, versatile in terms of denticity, tautomerism and the rotatable C-C bond.

Journal: :Berichte der deutschen chemischen Gesellschaft 1904

Journal: :Journal of the American Chemical Society 2017

Journal: :Berichte der deutschen chemischen Gesellschaft 1911

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