introduction: metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. the most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. renal cell carcinoma accounts for nearly 3% of all adult malignancies. it usually metastasizes to the lungs,...

BACKGROUND The distribution and kind of rat sarcoma viral oncogenes homolog (RAS) mutations, as well as their clinical impact on different types of thyroid lesions, vary widely among the different populations studied. We performed a comprehensive mutational survey in the highly related RAS genes HRAS, KRAS, and NRAS in a case series of proliferative thyroid lesions with known BRAF mutational st...

BACKGROUND Thyroid nodules are common among adults though only a small percentage is malignant, which can histologically mimic benign nodules. Accurate diagnosis of these thyroid nodules is critical for the proper clinical management. METHODS We investigated immunoexpression in 98 surgically removed benign thyroid nodules including 52 hyperplastic nodules (HN) and 46 follicular/Hurthle cell a...

this is a case report concerning a 60 years old man who lived for a short period in an endemic area of khuzestan province (neighboring province of persian gulf in iran) for approximately 20 years ago. recently he referred to the urology department of kerman university of medical sciences with hematuria and dysuria. in the sonography a polypoid mass on the bladder floor was observed. in the cyst...

background and aims. several diagnostic methods are being employed to detect benign and malignant lesions, one of which is silver nitrate staining for organizer regions. the number of nucleolar organizing regions (nors) can be used to show the degree of cell activity or metabolism in pathologic lesions. this study was designed to evaluate nors as determinants of precancerous and squamous cell c...

conclusions based on evidence, dentists and dental health care professionals should consider periodontal disease as a risk factor for the development of neoplasms in the oral cavity. it also seems a good idea to provide periodontal therapy for patients with cancer to achieve ideal therapeutic results. results cancer of the oral cavity and periodontal disease are related from different aspects. ...

With fewer than 40 cases described in the otolaryngology literature, mixed medullary papillary thyroid carcinoma represents a rare but phenotypically distinct tumor. While isolated medullary carcinoma may be admixed with normal follicular structures, true mixed carcinoma displays morphological and immunological characteristics of medullary and papillary carcinoma within a single lesion. We repo...