The Knowledge of variations in the lung can help surgeons to control bleeding during pulmonary lobectomy or might be used to reduce post-operative complications. Due to the importance of the knowledge of variations in lungs for clinicians, especially surgeons and radiologists, we report a case with lung lobe and fissure. During the autopsy of a 27-year-old man at the Legal Medicine Organizatio...

introduction: lung cancer is one of the leading causes of cancer related deaths in the world. the incidence of lung cancer is increasing in india and there is a need to understand the natural history of this disease. aim of the study: to study the clinico- pathological- radiological profile of patients diagnosed with lung cancer from january 2013 to may 2015 at a tertiary care teaching hospital...

Lung adenocarcinoma, the most commonly diagnosed type of lung cancer, has a poor prognosis even with combined surgery, chemotherapy, or molecular targeted therapies. Most patients are diagnosed with an in-operable advanced or metastatic disease, both pointing to the necessity of developing effective therapies for lung adenocarcinoma. Surfactant protein B (SP-B) has been found to be overexpresse...

The profiles of prostanoid biosynthesis from endogenous arachidonic acid in 16 established cell lines derived from 4 histological classes of human carcinomas were determined by capillary gas chromatography-mass spectrometry. Detectable quantities of prostanoids were isolated from the culture medium of cell lines representative of the different histological classes of human tumors: colorectal ad...

: Pseudoangiosarcomatous squamous cell carcinoma, also called pseudovascular, pseudoangiomatoid or adenoid pseudovascular is an uncommon and highly aggressive variant of carcinoma. Histologically, it characterized by proliferation atypical keratinocytes with acantholysis formation spaces, forming anastomosed channels lined neoplastic cells that invade the dermis. These are positive for cytokera...

From the ethanol extract of the stem of Lecaniodiscus cupanioides Planch, two known compounds 1 and 2 were isolated and identified as triterpenoid saponins 3-O-[α-L-arabinofuranosyl- (1→3)-α-L-rhamnopyranosyl- (1→2)-α-L-arabinopyranosyl-]-hederagenin and 3-O- [α-L-arabinopyranosyl- (1→3)-α-L-rhamnopyranosyl (1→2)-α-L-arabinopyranosyl-]-hederagenin. The structures were established by physicochem...

Generalized hypomethylation of the genome and of specific genes has been described in human tumors. We now report that in human lung cancers, especially in the most aggressive form, small cell lung carcinoma, and in lymphomas, the 5'-region of the calcitonin (CT) gene exhibits methylation of increased numbers of CCGG sites in comparison with normal adult tissues. These unusual methylation patte...

2 Imanishi K, Yanmaguchi K, Suzuki M, Honda S, Yanaihara N, Abe K. Production of transforming growth factor-cs in human tumor cell lines. Br J Cancer 1989 (in press) 3 Imanishi K, Yamaguchi K, Honda S. Abe K. Transforming growth factor-a as a possible autocrine growth factor for human adenocarcinoma of the lung. In: Imura H, Shizume K, Yoshida S, eds. Progress in endocrinology, 1988 vol 2. Amst...

A major impediment to the study of human lung cancer pathophysiology, as well as to the discovery and development of new specific antitumor agents for the treatment of lung cancer, has been the lack of appropriate experimental animal models. This paper describes a new model for the propagation of human lung tumor cells in the bronchioalveolar regions of the right lungs of athymic NCr-nu/nu mice...

3000 patients, having undergone fiber - optic bronchoscopy (foli) over 10 years, in our hospital were evaluated. thec aim of this study was to determine the prevalence of lung cancer in iran and their correlation with somking and to study the clinical anil radiological signs in different cancers ami the role of fiber-optic bronchoscopy in their diagnosis and the hazards of this method, 'llxe co...