Hinze, Harry C. (University of Wisconsin, Madison), and Duard L. Walker. Variation of herpes simplex virus in persistently infected tissue cultures. J. Bacteriol. 82:498-504. 1961.-Cultures of human conjunctiva, HeLa, and KB cells infected with herpes simplex virus (HF strain) were cultured for prolonged periods in medium containing low levels of antibody. After continuous culture of the infect...

Submit Manuscript | http://medcraveonline.com Abbreviations: AIDS: Acquired Immune Deficiency Syndrome; BCBL: Body Cavity Based Lymphoma Cell Line; CSWS: Commercial Sex Workers; DNA: Deoxyribonucleic Acid; EIA: Enzyme Immune Assays; ELISA: Enzyme Linked Immunosorbent Assays; FSWS: Female Sex Workers; HBV: Hepatitis B Virus; HCV: Hepatitis C Virus; HHV-8: Human Herpes Virus Type 8; HIV: Human Im...

Human herpes virus-8 (HHV-8)-associated primary effusion lymphoma (PEL) is an unusual lymphoma confined to the body cavities, which primarily affects human immunodeficiency virus (HIV)-positive men at high risk for Kaposi's sarcoma (KS). We describe two HIV-negative elderly Italian men, who developed pleural HHV-8-positive PEL in association with other diseases (systemic hypertension, colonic c...

acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. acycloviris converted to the monophosphate by thymidine kinase the virus-specific form of this enzyme and is subsequently converted to the triphosphate by the host cell kinase. acyclovir triphosphate inhibits viral dna-polymerase terminating the chain and...

ulcerative colitis (uc) is one type of inflammatory bowel disease (ibd). herpes viruses have been suggested as possible etiological agents of uc and crohn’s disease (cd). the aim of this study was to investigate the prevalence of herpes simplex virus (hsv), cytomegalovirus (cmv) and epstein-barr virus (ebv) in patients with uc in comparison with healthy subjects by using pcr technique. in this ...

OBJECTIVE To investigate the association between cerebral palsy and direct evidence for perinatal exposure to neurotropic viruses. DESIGN Population based case-control study. SETTING Adelaide Women's and Children's Hospital Research Laboratory. PARTICIPANTS AND MAIN OUTCOME MEASURES Newborn screening cards of 443 white case patients with cerebral palsy and 883 white controls were tested f...

OBJECTIVE To report the frequency of coexisting herpes viruses (herpes simplex virus 1 [HSV-1] or HSV-2, varicella zoster virus, Epstein-Barr virus [EBV], cytomegalovirus, or human herpes virus 6 [HHV-6]) and autoantibodies in patients with encephalitis (herpes or autoimmune) in clinical laboratory service. METHODS Three groups were evaluated for herpes viruses and antibodies: group 1-patient...

Pretreatment of human fibroblast cultures with human leukocyte interferon (HIF, 1,000 IU/ml) resulted in a 24-h delay of virus replication after infection with vaccinia virus and herpes simplex virus type 1 and type 2. Additional HIF treatment 24 h after infection effectively lowered the maximum yield of viral infectivity. Equal results were obtained in simian cells with 3,000 IU of HIF per ml....

In the preceding experiments observations have been reported upon the nature of herpes virus which confirm the suspicion that the virus is intracellularly located in the infected nervous system. In regard to the immunological conditions existing in this disease, our experiments have reaffirmed that herpes virus can be neutralized with the serum of actively immunized animals and have offered an ...

Viral meningitis is a common infectious disease of the central nervous system (CNS) that occurs worldwide. The aim of this study was to identify the etiologic agent of lymphomonocytary meningitis in Curitiba, PR, Brazil. During the period of July 2005 to December 2006, 460 cerebrospinal fluid (CSF) samples with lymphomonocytary meningitis were analyzed by PCR methodologies. Fifty nine (12.8%) s...