نتایج جستجو برای: human calcitonin
تعداد نتایج: 1647951 فیلتر نتایج به سال:
In cartilaginous fish, two cDNAs encoding calcitonin-family receptors were isolated for the first time from the stingray brain. The open reading frame of one receptor cDNA coded a 525-amino acid protein. The amino acid identity of this receptor to human calcitonin-receptor-like receptor (CRLR) is 64.5%, frog CRLR is 64.7%, and flounder CRLR is 61.2% and this was higher than to human calcitonin ...
Calcitonin gene-related peptide, a product of the calcitonin gene, is a potent vasodilator neuropeptide. We have demonstrated that dietary calcium deficiency decreased the neuronal (laminae I/II of the dorsal horn of the spinal cord) content of immunoreactive calcitonin gene-related peptide in the normal rat. Neuronal calcitonin gene-related peptide levels are also reduced in the spontaneously ...
Human procalcitonin (PCT) is a peptide precursor of the calcium-regulating hormone calcitonin. Traditionally, PCT has been used as biomarker for severe bacterial infections and sepsis. It also recently identified potential marker COVID-19. Normally, serum intracellularly cleaved to calcitonin, which lowers levels (<0.01 ng/mL). In infectious diseases sepsis, increase above 100 ng/mL in respo...
conclusions it seems that nasal spray of calcitonin can effectively improve qol of women with lbd and qol changes were not influenced by clinical or para-clinical alteration. mental health domain must be more considered in further studies as a predicting domain for health-related quality of life (hr-qol) changes. background physical activity and mental health could be affected by osteoporosis a...
To assess whether calcitonin is important in maintaining the integrity of bone the calcitonin gene of a young male patient with osteoporosis and no detectable plasma concentrations of calcitonin was studied. Genomic Southern blots with various restriction enzymes showed no large abnormalities in his calcitonin gene. Genomic clones representing his calcitonin gene were then analysed. His gene en...
Amyloid fibrils were studied from two different tissues of medullary carcinoma of the thyroid (MCT). The fibrils mainly consisted of a low molecular weight protein, AMCT, which was immunologically distinct and did not react with various antisera against known amyloid fibril proteins. A specific antiserum raised against the MCT amyloid proteins gave a reaction of identity with the degraded MCT a...
A sensitive, specific radioimmunoassay of calcitonin is described, suitable for measuring the hormone in peripheral plasma of normal man. With this assay we have demonstrated that calcitonin is detectable under basal Conditions and the concentrations respond to induced, and spontaneous hypercalcemia and induced hypocalcemia. The mean value for basal calcitonin of normal men was 182 pg/mI (range...
Introduction: Various therapeutic options such as Calcitonin are suggested for patients with low bone density. However, the efficacy remains uncertain in all patients. C-telopeptide of type I collagen (CTx) is the authentic bone marker which is recently used to assess the bone turnover. This study aimed at revealing the therapeutic effects of Calcitonin on osteopenic women via ...
Calcitonin is an important physiological regulator of salmon gills. Although the calcitonin receptor was found in salmon gills, the critical question concerning the source of the hormone remained unanswered. In this communication, evidence is presented for expression of calcitonin mRNA and its encoded peptide in gills of the pink salmon, Oncorhynchus gorbuscha. The expression of calcitonin gene...
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