نتایج جستجو برای: hsp25

تعداد نتایج: 193  

Journal: :The Journal of biological chemistry 1999
O Heidenreich A Neininger G Schratt R Zinck M A Cahill K Engel A Kotlyarov R Kraft S Kostka M Gaestel A Nordheim

Several growth factor- and calcium-regulated kinases such as pp90(rsk) or CaM kinase IV can phosphorylate the transcription factor serum response factor (SRF) at serine 103 (Ser-103). However, it is unknown whether stress-regulated kinases can also phosphorylate SRF. We show that treatment of cells with anisomycin, arsenite, sodium fluoride, or tetrafluoroaluminate induces phosphorylation of SR...

Journal: :Biochemical Society transactions 2002
A Kotlyarov M Gaestel

The phenotype of mitogen-activated protein kinase-activated protein kinase-2 (MK2) knockout mice revealed the essential role of this enzyme in post-transcriptional regulation of lipopolysaccharide-induced expression of cytokines such as tumour necrosis factor (TNF)-alpha, interleukin-6 and interferon-gamma, at the level of mRNA stability and translation. In the case of TNF-alpha, this regulatio...

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