Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is the causative agent of hemorrhagic colitis and hemolytic uremic syndrome in humans. However, the bacterium can colonize the intestines of ruminants without causing clinical signs. EHEC O157:H7 needs flagella (H7) and hemorrhagic coli pili (HCP) to adhere to epithelial cells. Then the bacterium uses the translocated intimin receptor (Tir) and ...

allogeneic hematopoietic stem cell transplantation (hsct) is a curative treatment option for hematological disorders. cyclosporine (csa) is one of the major immunosuppressive agents for the prophylaxis against graft versus host disease (gvhd). in this retrospective study, we evaluated the effects of csa serum levels on the incidence of acute gvhd and transplant outcomes. 103 adult patients rece...

Recombinant adeno-associated viruses (rAAV) are the gene transfer vector of choice for many in vivo therapies. These vectors synthetic viral particles which can deliver a therapeutic to patient or patients’ cells correct genetic abnormality. be produced in single-use bioreactors and purified using scalable technologies. We evaluated use scalable, filtration chromatography technologies do...

background: interferons with diffrent functions such as antiviral, antiproliferative and immunomodulatory actions are effctivemedications for a number of diseases. one of these new interferons (ifns) is interleukin-29 (il-29) belongs to the family of ifn-λ hasantiviral activity and its potent in accompanying with ifn-α in treatment of hcv infection has been evaluated (clinical trial phase ii).r...

An intracellular multiplication F (IcmF) family protein is a conserved component of a newly identified type VI secretion system (T6SS) encoded in many animal and plant-associated Proteobacteria. We have previously identified ImpL(M), an IcmF family protein that is required for the secretion of the T6SS substrate hemolysin-coregulated protein (Hcp) from the plant-pathogenic bacterium Agrobacteri...

This paper presents a feasibility study on a real-time in field pest classification system design based on Blackfin DSP and 3G wireless communication technology. This prototype system is composed of remote on-line classification platform (ROCP), which uses a digital signal processor (DSP) as a core CPU, and a host control platform (HCP). The ROCP is in charge of acquiring the pest image, extrac...