Despite new minimally invasive techniques, cardiopulmonary bypass (CPB) is still necessary for many major operations in the field of cardiac surgery. Unwanted side effects of CPB are well known but poorly understood. We therefore developed a rodent model to study the pathophysiology of these potential complications. Male Fischer rats were anaesthetized, intubated and ventilated. The carotid art...

Treatment with bioartificial kidneys had beneficial effects in animal experiments and improved survival of critically ill patients with acute kidney injury in a Phase II clinical trial. However, a Phase II b clinical trial failed. This and other results suggested various problems with the current design of bioartificial kidneys. We propose a novel design to improve various properties of device,...

Hollow fibre cell fishing with HPLC (HFCF-HPLC) based on the human ovarian cancer cell line SKOV-3, human renal tubular cell line ACHN or hepatoma cell line HepG-2 was employed to screen active groups of coumarin and volatile oil in Radix angelicae sinensis, Radix angelicae dahuricae and Fructus citri sarcodactylis. Simultaneously, hollow fibre liquid phase microextraction with HPLC (HFLPME-HPL...

In cylindrical continua, hoop stresses are induced due to the circumferential failure. This mainly happens when the cylinder is subjected to mechanical loads which vary in the circumferential directions. On the other hand, radial stress is stress in the direction of or opposite to the central axis of a cylindrical body. In the present study, the influence of curvilinear anisotropy on the radial...

Propagation time through an optical fibre changes with the environment, e.g., a change in temperature alters the fibre length and its refractive index. These changes have negligible impact in many key fibre applications, e.g., telecommunications, however, they can be detrimental in many others. Examples are fibre-based interferometry (e.g., for precise measurement and sensing) and fibre-based t...

This paper demonstrates the first mode-multiplexed system over 19-cell hollow-core photonic band gap fibre, at 2×20Gbps using the LP0,1 and LP2,1-like modes. OCIS codes: 060.0060 (Fiber optics and optical communications), 060.5295 (Photonic crystal fibers)

Membrane processes allow scalable and energy-efficient separation of gas liquid, advance low-carbon purifications in various industrial environmental applications enable more resilient economy society. In pursuit developing advanced membranes with continuously improved separating performances, nanofillers have been commonly incorporated into to upgrade membrane properties such as mechanical rob...