Bayesian networks are emerging into the genomic arena as a general modeling tool able to unravel the cellular mechanism, to identify genotypes that confer susceptibility to disease, and to lead to diagnostic models. This chapter reviews the foundations of Bayesian networks and shows their application to the analysis of various types of genomic data, from genomic markers to gene expression data....

Computer applications to storm runoff prediction have revolutionized the watershed modeling techniques. In general, a watershed is modeled as a system with inputs and outputs (Chow 1964). A system can be lumped or distributed, depending upon the spatial and temporal characteristics of the design variables used in the model. A lumped parameter ignores the variability in space. On the other hand,...

The 2003 flood of the Muda River reached 1,340 m3 /s at Ladang Victoria and adversely impacted 45,000 people in Malaysia. A flood control remediation plan proposed a levee height based on a 50-year discharge of 1 ,815 m3 /s obtained from hydrologic models. This design discharge falls outside the 95% confidence intervals of the flood frequency analysis based on field measurements. Instream sand ...

Joshua Peschel, Texas A&M University JOSHUA M. PESCHEL is a PhD student in Civil Engineering at Texas A&M University. He received the BS in Biological Systems Engineering and the MS in Biological & Agricultural Engineering, also from Texas A&M. His current research interests include unsaturated soil water transport, spatially-distributed hydrologic modeling, and emerging technologies in enginee...

Myoepithelial cells, which surround ducts and acini of glandular organs, form a natural border separating proliferating epithelial cells from basement membrane and underlying stroma. Myoepithelial cells in situ and in vitro constitutively express high amounts of proteinase inhibitors that include tissue inhibitor of metalloproteinase 1, protease nexin-II, alpha-1 antitrypsin, and maspin. Human ...

The beamforming capabilities of conformal cylindrical Huygens metasurface (HMS) coatings for linear antennas are assessed. It is shown that by engineering the phase-gradient profile HMS, original omnidirectional radiation pattern antenna can be shaped to form multi- or single-beam configurations. A closed-form expression phase-insertion coating required achieve desired derived, and several full...

A radiometric micro-volume procedure for measurement of erythrocytic hexose monophosphate shunt (HMS) activity in intact cells in vitro is described. The procedure is rapid, allowing 200 individual HMS determinations in a single experiment of 5 hr duration. The procedure is reproducible, yielding HMS activity means insignificantly different (P greater than 0.05) between replicate experiments. A...

1Department of Radiology, European Institute of Oncology, Milan, Italy 2Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy 3Department of Hematology/Oncology and Department of Radiology, Boston Children’s Hospital, Boston, MA, USA 4Department of Radiology, University of Massachusetts Medical School and University of Massachusetts Memorial Medical Center, Worcester, MA,...

Floods are one of the most destructive natural hazards in Pakistan, causing significant damage. During monsoons, when westerly winds and concentrated rainfall occur rivers’ catchments, floods become unmanageable. Given limited resources there has been minimal effort to quantify amount runoff generated by ungauged catchments. In this study, ten hill torrents Koh e Suleiman (District Rajanpur DG ...

While prior research reported altered fuel utilization stemming from pre-exercise modified starch ingestion, the practical value of this starch for endurance athletes who consume carbohydrates both before and during exercise is yet to be examined. The purpose of this study was to determine the effects of ingesting a hydrothermally-modified starch supplement (HMS) before and during cycling on pe...