نتایج جستجو برای: histone modification
تعداد نتایج: 166360 فیلتر نتایج به سال:
Cancer is caused by aberrant genetic and epigenetic changes in genes expression. DNA methylation, histone modification, and microRNAs gene deregulation are the most known epigenetic changes in different stages of cancer. Since every tumor has its own specific epigenome, any abnormal pattern is a potential biomarker for classification of different types of tumors. Despite, tumorigenesis, abnorma...
Gcn5 is a histone modification enzyme that performs its function by global or locus-specific histone acetylation. It is known that Gcn5 involves in stress responses in yeast. Our previous data showed that Gcn5 relocalized to the long genes under IM KCl stress conditions in yeast. Here we use a stress adaptation and recovery model and performed 52 microarrays. By investigating the gene regulatio...
Recent advances demonstrate that epigenome changes can also cause phenotypic diversity and can be heritable across generations, indicating that they may play an important role in evolutionary processes. In this study, we analyzed the chromosomal distribution of several histone modifications in five elite maize cultivars (B73, Mo17, Chang7-2, Zheng58, ZD958) and their two wild relatives (Zea may...
Nucleosomes can be covalently modified by addition of various chemical groups on several of their exposed histone amino acids. These modifications are added and removed by enzymes (writers) and can be recognized by nucleosome-binding proteins (readers). Linking a reader domain and a writer domain that recognize and create the same modification state should allow nucleosomes in a particular modi...
Hang Zhang, Xiao-Jun Tian, Abhishek Mukhopadhyay, Kenneth S. Kim, Jianhua Xing 1, Department of Biological Sciences, Virginia Tech, Blacksburg, Virginia, 24061-0406, USA 2, Department of Physics, Virginia Tech, Blacksburg, Virginia, 24061-0406, USA 3, Lawrence Livermore National Laboratory and University of California, Livermore, California, USA 4, Beijing Computational Science Research Center,...
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