Here, we report the complete genome sequence of Moorella thermoacetica DSM 2955(T), an acetogenic bacterium, which uses the Wood-Ljungdahl pathway for reduction of H2 + CO2 or CO. The genome consists of a single circular chromosome (2.62 Mb).

We prepared a model of experimental peritonitis by introducing Escherichia coli into the peritoneal cavity of the histamine-deficient mice generated by a disruption of the gene for histidine decarboxylase (HDC), the unique histamine-synthesizing enzyme. When we inoculated E. coli into the peritoneal cavities of the HDC(-/-) (histamine-deficient) mice, they eliminated E. coli more efficiently th...

Histamine-producing bacteria (HPB) such as Photobacterium phosphoreum and Raoultella planticola possess histidine decarboxylase (HDC), which converts histidine into histamine. Histamine fish poisoning (HFP) is attributable to the ingestion of fish containing high levels of histamine produced by HPB. Because freezing greatly decreases the histamine-producing ability of HPB, especially of P. phos...

For asthma sufferers, contracting a lung infection can mean hospitalization, but it has never been clear how bugs exacerbate allergic conditions. Xu et al. (page 2907) now show that the major allergic inflammatory mediator— histamine—is also produced in response to infection. But it comes from an unexpected source. Mast cells together with basophils are considered the major producers of hista-m...

The formation of mannitol in fermenting mixtures of plant, origin is now known to be due to a group of bacteria which act upon fructose and reduce this sugar to its corresponding alcohol. Mannitol-forming bacteria have been found in wine, sauerkraut, silage, canned goods, yeast, and cereal infusions. In some of t,hcse products such as sauerkraut and silage, their presence is not, objectionable,...

Nasal provocation tests with histamine and methacholine were carried out on 25 healthy men in an effort to assess the dynamic changes of albumin, total IgA, secretory IgA and lactoferrin concentrations in the nasal secretion. The trials were performed with 0.5, 1, and 4 mg of histamine and 8, 16, and 32 mg of methacholine. Each dose of histamine or methacholine was sprayed into the nose every 2...

For asthma sufferers, contracting a lung infection can mean hospitalization, but it has never been clear how bugs exacerbate allergic conditions. Xu et al. (page 2907) now show that the major allergic inflammatory mediator— histamine—is also produced in response to infection. But it comes from an unexpected source. Mast cells together with basophils are considered the major producers of hista-m...

Spleen cells from mice immunized with sheep red cells were separated by differential adherence to insolubilized histamine, catecholamines, and prostaglandins. The hormones were insolubilized by linking them to Sepharose beads through a protein carrier. We measured hemolytic plaque formation (per million splenic leukocytes) of cells which passed through columns of hormone-carrier-Sepharose beads...

objective: crocin and safranal, as the major constituents of saffron, have many biological activities. this study investigated the effects of crocin and safranal on yawning response induced by intracerebroventricular (i.c.v.) injection of histamine in rats. materials and methods: in ketamine/xylazine-anesthetized rats, a guide cannula was implanted in the right ventricle of the brain and yawnin...