OBJECTIVE The Diabetes Prevention Program (DPP) reported no racial/ethnic differences in the incidence of diabetes in individuals with impaired glucose tolerance (IGT). Therefore, it has been hypothesized that factors associated with racial/ethnic disparities act prior to the development of IGT. Because impaired fasting glucose (IFG) and obesity were also very prevalent in the DPP, we examined ...

We report a genome-wide association study (GWAS) and admixture analysis of glaucoma in 12 008 African-American and Hispanic women (age 50-79 years) from the Women's Health Initiative (WHI). Although GWAS of glaucoma have been conducted on several populations, this is the first to look at glaucoma in individuals of African-American and Hispanic race/ethnicity. Prevalent and incident glaucoma was...

BACKGROUND We sought to identify the age-adjusted incidence of lower-extremity amputation (LEA) in Mexican Americans, blacks, and non-Hispanic whites with diabetes in south Texas. METHODS We summarized medical records for hospitalizations for LEAs for 1993 in six metropolitan statistical areas in south Texas. RESULTS Age-adjusted incidence per 10,000 patients with diabetes was 146.59 in bla...

BACKGROUND Although age-adjusted incidence rates (per 100,000) for melanoma are lower among Hispanics and blacks (4.5 and 1.0, respectively) compared with white non-Hispanics (21.6), melanomas among minority populations in the United States are more likely to metastasize and have poorer outcomes. METHODS A review of the literature was conducted on melanomas affecting Hispanic and black Americ...

Traumatic events like September 11 and Hurricanes Katrina and Rita (H-KR) have heightened national awareness on the effects that such events can have on communities and specific populations. These disasters not only had major effects on those directly impacted by the hurricane, but also on first responders and the subsequent teams of personnel who provided aid to residents and evacuees. Student...

Type 2 diabetes makes a compelling case study for public health action (1). The disease respects no boundaries. It is increasingly common — occurring in both developed and developing countries (2), in men and women, at earlier ages than in past decades, and in persons of every race and ethnic group, with a high prevalence in Hispanic/Latino Americans and in other minority groups, including nonH...

OBJECTIVE To test the hypothesis that clinical observations made at patient presentation can distinguish type 2 diabetes (T2D) from type 1 diabetes (T1D) in pediatric patients aged 2 to 18. SUBJECTS AND METHODS Medical records of 227 African American and 112 Hispanic American pediatric patients diagnosed as T1D or T2D were examined to compare parameters in the two diseases. Age at presentatio...

OBJECTIVE To estimate allele frequencies and the marginal and combined effects of novel fasting glucose (FG)-associated single nucleotide polymorphisms (SNPs) on FG levels and on risk of impaired FG (IFG) among non-Hispanic white, non-Hispanic black, and Mexican Americans. RESEARCH DESIGN AND METHODS DNA samples from 3,024 adult fasting participants in the National Health and Nutrition Examin...