The purpose of this study was to determine whether the maximum shortening velocity (Vmax) in Hill's mechanical model (A. V. Hill. Proc. R. Soc. London Ser. B. 126: 136-195, 1938) should be scaled with activation, measured as a fraction of the maximum isometric force (Fmax). By using the quick-release method, force-velocity (F-V) relationships of the wrist flexors were gathered at five different...

cAMP-activated Na+ current (INa,cAMP) was studied in voltage-clamped neurons of the seaslug Pleurobranchaea californica. The current response to injected cAMP varied in both time course and amplitude as the tip of an intracellular injection electrode was moved from the periphery to the center of the neuron soma. The latency from injection to peak response was dependent on the amount of cAMP inj...

We find sets of solutions to the generalized spheroidal wave equation (GSWE) or, equivalently, to the confluent Heun equation. Each set is constituted by three solutions, one given by a series of ascending powers of the independent variable, and the others by series of regular and irregular confluent hypergeometric functions. For a fixed set, the solutions converge over different regions of the...

This work established strain-based forming limit diagrams (FLDs) for DP600 steel sheets by means of experimental investigation and theoretical prediction. The results showed that compared to the curve (FLC), predicted Keeler equation, FLCs Hill’79 yield criterion, or Logan-Hosford were more suitable predicting sheets. Solutions from analytical methods FLD, based on combining uniaxial tensile te...

Oxygen binds to hemoglobin cooperatively, and a correct description of this binding is relevant not only for understanding the mechanisms involved molecular processes but also clinical purposes. Hill’s equation, derived over hundred years ago, still simplest most efficient way perform description. However, in terms accuracy, it inferior Adair´s which contains more parameters. We proposed use mo...