Classic Epidemiology: High-Density Lipoprotein Cholesterol Is a Biomarker of Atherogenic Lipoproteins and Other Major Cardiovascular Risk Factors High-density lipoprotein (HDL) cholesterol is a robust biomarker of atherosclerotic cardiovascular disease (CVD) events. In observational studies and many clinical trials of statin therapy, HDL cholesterol levels are inversely associated with CVD even...

High-density lipoprotein (HDL) is a lipid and protein complex that consists of apolipoproteins and lower level HDL-associated enzymes. HDL dysfunction is a factor in atherosclerosis and decreases patient survival. Mass spectrometry- (MS-) based proteomics provides a high throughput approach for analyzing the composition and modifications of complex HDL proteins in diseases. HDL can be separated...

background: urtica dioica has been used as antihypertensive, antihyperlipidemic and antidiabetic herbal medicine. the purpose of this study was to study the effect of hydroalcoholic extract of urtica dioica on fructose-induced insulin resistance rats. methods: forty male wistar rats were randomly divided into five groups including control, fructose, extract 50, extract 100 and extract 200. the ...

BACKGROUND AND AIM Dyslipidaemia is the main risk factor for coronary heart disease (CHD). Plasma lipid levels are conven-tionally used to predict coronary risk globally, but further studies are required to investigate whether the lipoprotein ratios are superior to conventional lipid parameters as predictors for CHD. METHODS A hospital-based case-control study consisting of 738 CHD patients a...

High-density lipoprotein (HDL) provides a pathway for the passage of lipid peroxides and lysophospholipids to the liver via hepatic scavenger receptors. Perhaps more importantly, HDL actually metabolizes lipid hydroperoxides preventing their accumulation on low-density lipoprotein (LDL), thus impeding its atherogenic structural modification. A number of candidates have been suggested to be resp...

Classic Epidemiology: High-Density Lipoprotein Cholesterol Is a Biomarker of Atherogenic Lipoproteins and Other Major Cardiovascular Risk Factors High-density lipoprotein (HDL) cholesterol is a robust biomarker of atherosclerotic cardiovascular disease (CVD) events. In observational studies and many clinical trials of statin therapy, HDL cholesterol levels are inversely associated with CVD even...

The term plasma lipid profile considers measurement of certain components of plasma including total cholesterol (TCh), high density lipoprotein cholesterol (HDL-Ch), triglycerides (Tg), low density blipoprotein cholesterol (LDL-Ch) and very low density lipoprotein cholesterol (VLDL-Ch). TCh consists of all the cholesterol present in different lipoproteins like high density lipoprotein (HDL), lo...

We investigated the relation of plasma lipids to the risk for ischemic stroke by comparing clinical and biochemical characteristics of survivors of cortical (n = 48) and lacunar (n = 36) brain infarction. By analysis of variance, no differences were observed in the concentrations of total cholesterol, triglycerides, low density lipoprotein cholesterol, very low density lipoprotein cholesterol, ...

Purpose To evaluate lipids and C-reactive protein serum levels in patients with pseudoexfoliation syndrome (PEX) in the Polish population. Methods 96 patients were studied with PEX and 79 control subjects. Total cholesterol, triglycerides, high-density lipoprotein (HDL)-cholesterol, low-density lipoprotein (LDL)-cholesterol, non-HDL-cholesterol and CRP serum levels, and TG/HDL-C and TC/HDL-C ...

OBJECTIVE HIV patients on antiretroviral therapy (HIV/ART) exhibit a unique atherogenic dyslipidemic profile with hypertriglyceridemia (HTG) and low plasma concentrations of high-density lipoprotein (HDL) cholesterol. In the Heart Positive Study of HIV/ART patients, a hypolipidemic therapy of fenofibrate, niacin, diet, and exercise reduced HTG and plasma non-HDL cholesterol concentrations and r...