We propose some improvements of the Multiple Birth and Cut algorithm (MBC) in order to extract nuclei in 2D and 3D images. This algorithm based on marked point processes was proposed recently in (Gamal Eldin et al., 2012). We introduce a new contrast invariant energy that is robust to degradations encountered in fluorescence microscopy (e.g. local radiometry attenuations). Another contribution ...

in this paper, we consider a flow shop scheduling problem with availability constraints (fsspac) for the objective of minimizing the makespan. in such a problem, machines are not continuously available for processing jobs due to preventive maintenance activities. we proposed a mixed-integer linear programming (milp) model for this problem which can generate non-permutation schedules. furthermor...

one of the most important extensions of the capacitated vehicle routing problem (cvrp) is the vehicle routing problem with simultaneous pickup and delivery (vrpspd) where customers require simultaneous delivery and pick-up service. in this paper, we propose an effective ant colony optimization (eaco) which includes insert, swap and 2-opt moves for solving vrpspd that is different with common an...

The human has always been to find the best in all things. This Perfectionism has led to the creation of optimization methods. The goal of optimization is to determine the variables and find the best acceptable answer Due to the limitations of the problem, So that the objective function is minimum or maximum. One of the ways inaccurate optimization is meta-heuristics so that Inspired by nature, ...

In this paper, a mixed-integer linear programming model is proposed to integrate batch picking and distribution scheduling problems in order to optimize them simultaneously in an order picking warehouse. A tow-phase heuristic algorithm is presented to solve it in reasonable time. The first phase uses a genetic algorithm to evaluate and select permutations of the given set of customers. The seco...

We propose some improvements of the Multiple Birth and Cut algorithm (MBC) in order to extract nuclei in 2D and 3D images. This algorithm based on marked point processes was proposed recently in (Gamal Eldin et al., 2012). We introduce a new contrast invariant energy that is robust to degradations encountered in fluorescence microscopy (e.g. local radiometry attenuations). Another contribution ...

For many real-world problems, there exist non-deterministic heuristics which generate valid but possibly sub-optimal solutions. The program optimisation with dependency injection method, introduced here, allows such a heuristic to be placed under evolutionary control, allowing search for the optimum. Essentially, the heuristic is “fooled” into using a genome, supplied by a genetic algorithm, in...

Generating piecewise linear approximations of digitized or "densely sampled" curves is an important problem in image processing, pattern recognition, geometric modeling, and computer graphics. Even though much attention bas been paid to the planar curve case, little work has addressed space curve approximation. In this paper, we consider how to approximate an arbitrary digitized 3-D space CUnlC...

Group A Streptococcus (GAS) can be internalized by epithelial cells, including keratinocytes from human skin or pharyngeal epithelium. Internalization of GAS by epithelial cells has been postulated both to play a role in host defense and to provide a sanctuary site for GAS survival. The cholesterol-binding cytolysin streptolysin O (SLO) appears to enhance virulence in part by inhibiting GAS int...

The vehicle routing problem with the capacity constraints was considered in this paper. It is quite difficult to achieve an optimal solution with traditional optimization methods by reason of the high computational complexity for large-scale problems. Consequently, new heuristic or metaheuristic approaches have been developed to solve this problem. In this paper, we constructed a new heuristic ...