the three cases of infection not transmitted by transfusion all the donors were negative for hepatitis B core antibody. Blood donations are accepted by the National Blood Transfusion Service 12 months after an episode of jaundice or hepatitis in the donor so long as testing for hepatitis B surface antigen yields negative results. In the light of our findings and recent legislation relating to p...

Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the p...

OBJECTIVE The aim of this study is to evaluate the clinical and prognostic values of persistence of anti-hepatitis B core immunoglobulin M antibody in asymptomatic adults chronic hepatitis B surface antigen anti-hepatitis Be carriers and its absence in others. METHODS Fifty-two hepatitis B surface antigen/anti-hepatitis Be carriers with and 32 without anti-hepatitis B core immunoglobulin M ma...

conclusions fluctuations in serum alt levels may change the prognosis of a hbv inactive carrier state. objectives this study aimed to determine the incidence rate and patterns of alt fluctuations and prognostic values for the development of chronic hbv e antigen (hbeag)-negative hepatitis b (chb), hbv surface antigen (hbsag) seroclearance, and liver-related complications. patients and methods t...

Routine use of the automated chemiluminescent microparticle immunoassay Abbott ARCHITECT anti-HBc for diagnosis of hepatitis B is limited in case of borderline reactive sera with low signal close to the cut-off index. In order to determine the significance of anti-HBc detection when borderline reactivity occurs using the ARCHITECT anti-HBc assay, a comparative study was designed. 3540 serum sam...

background: hepatitis b virus (hbv) infection is the most common cause of end-stage liver disease in iran. more than 70% of cases are negative for the hepatitis b e antigen (hbeag) and have a long-term response to antiviral therapy, as well as a high relapse rate after discontinuing lamivudine or interferon. these features could be due, in part, to genetic variation of the hbv genome. materials...