results of 351 patients, 76 patients (group 1) had a strong positive result for salivary occult blood test and 275 patients (group 2) had weak positive or negative test results. significant factors between the groups were obesity, level of ast, alt, ldh, alp, alb, d.bil, t.cho, afp, platelets (plt), iri, homa-ir, current interferon (ifn) treatment and the daily frequency of tooth brushing. betw...

The precise role of the poly(A) tail at the 3' end of the picornavirus RNA genome and the cellular factors that control its homeostasis are unknown. To assess the importance of the poly(A) tail for virus replication, the genome of the slowly replicating hepatitis A virus (HAV) with and without a poly(A) tail was studied after transfection into cells maintained under various conditions. A taille...

Objective(s): Hepatitis B virus infection causes chronic disease such as cirrhosis and hepatocellular carcinoma. The metabolomics investigations have been demonstrated to be related to pathophysiologic mechanisms in many disorders such as hepatitis B infection. The aim of this study was to investigate the saliva metabolic profile of patients with chronic hepatitis B in...

In this study a label-free electrochemical Immunosensor for ultrasensitive detection of Hepatitis C virus core antigen in serum samples was fabricated by using a simple approach. In this method a low-cost and sensitive immunosensor was fabricated based on a boehmite nanoparticles (BNPs) modified glassy carbon. The BNPs provide a specific platform with increased surface area which is capable of ...

Abstract Background: Distribution of hepatitis C virus genotypes varies geographically and can be associated with clinical aspects. The virus has six major genotypes and eleven sub-genotypes. According to the recent studies, in hepatitis C patients, treatment duration and ribavirin dosage should be determined based on the type of virus genotype. Be...

conclusions the results showed a declining trend in anti-hbsab titers over the time after vaccination against hepatitis b virus in our region. further studies are warranted to establish the need for a booster dose in cases that are at risk of hepatitis b virus infection. results hepatitis b seroprotection rates (anti hbsab ≥ 10 iu/l) among vaccinated children and adolescents aged 1 and 18 years...

This retrospective study compares the clinical features, laboratory profile and complications of anti HAV IgM positive acute viral hepatitis A in 138 children between 1-15 year (1-5 year: n=31; 5-10 year: n=85; and 10-15 year: n=22). We found that older children presented with HAV (hepatitis A virus) infection with more atypical manifestations (ascites and splenomegaly) and complications.

introduction: blood derived products have been known as an effective treatment for many years. however, this treatment is not without risk of infections transmission including hepatitis b virus (hbv) and hepatitis c virus (hcv) and human immune-deficiency virus (hiv) in people who received the blood. nevertheless, due to a high risk of blood born diseases through blood transfusion, screening fo...

background: sen virus (senv) is the latest virus proposed as a cause of unknown hepatitis cases. among nine detected genotypes of the virus, genotypes d and h are more frequent in hepatitis cases of unknown origin. the aim of this study was to determine the frequency of senv-d and senv-h genotypes in the sera of healthy individuals and hepatitis b and c patients. methods: totally, 200 serum sam...

today, chronic viral hepatitis is considered as a public health problem in the world. totally, 5% of the world population, especially in asia and africa suffer from this problem. the prevalence of acute hepatitis in america is 0.1-0.2 percent, 50% of those with hepatitis c (hcv) and 5-10% of them with hepatitis b (hcv) develop chronic hepatitis. determining hbv and hcv genotypes is important to...