background : there is disagreement on the effect of diabetes on oral hygiene. the purpose of this study was to assess the oral health and hygiene status of type 1 diabetic patient. methods : in this case control study, periodontal health and hygiene of 80 children and adolescents (5–18 yr of age) with type 1 diabetes mellitus referred to pediatric endocrine clinic of besat hospital hamadan iran...

background: sickle cell disease is a genetic disorder of hemoglobin causing myriad of pathology including anemia. the purpose of this study was to evaluate the baseline values of steady state hemoglobin and packed cell volume as a guide to managing the early recognition of hemolytic crises in sickle cell anemia. methods: a cross-sectional study was conducted among the sickle cell patients atten...

By using the technique of recoil-free absorption (Mössbauer effect) in iron, we found large amounts of iron, yielding a well-defined spectrum different from that of oxy- or deoxyhemoglobin, in whole erythrocytes of 13 patients with beta-thalassemia major and intermedia, 3 with hemoglobin H disease, 2 with sickle-cell anemia, and 1 with unstable hemoglobin Hammersmith. The Mössbauer spectra at v...

Abstract Inflammation’s impact on inflammatory bowel diseases is mostly due to altered non-coding RNA expression. This study aimed explore the rs2107425 polymorphism in long gene H19 (lncRNA H-19) and emphasize involvement of miR-200a lncRNA H-19 expression ulcerative colitis (UC) Crohn’s disease (CD). One hundred ten participants, ranging age from 22 58 years, participated current investigatio...

α-Thalassemia mutations affect up to 5% of the world's population. The clinical spectrum ranges from an asymptomatic condition to a fatal in utero disease. Hemoglobin H disease results from mutations of three α-globin genes. Deletional forms result in a relatively mild anemia, whereas nondeletional mutations result in a moderate to severe disease characterized by ineffective erythropoiesis, rec...