Rev Bras Hematol Hemoter. 2011;33(4):250-8 3. Liu Z, Cumberland WG, Hultin LE, Prince HE, Detels R, Giorgi JV. Elevated CD38 antigen expression on CD8+ T cells is a stronger marker for the risk of chronic HIV disease progression to AIDS and death in the Multicenter AIDS Cohort Study than CD4+ cell count, soluble immune activation markers, or combinations of HLA-DR and CD38 expression. J Acquir ...

Objectives: The hematological changes associated with acute malaria are well recognized. This study was conducted to assess and compare the incidence and severity of hematological changes in various types of malaria in adult population. Methodology: This observational study included 133 acute malaria patients admitted in the Infectious Diseases Unit of Rashid Hospital Dubai (JCI accredited) UAE...

The Agency for Toxic Substances and Disease Reg­ istry (ATSDR) derives minimal risk levels (MRLs) to assist in evaluating risk of adverse health effects in individuals exposed to hazardous substances. MRLs are derived from published values identifying no-ob­ served-adverse-effect levels (NOAELs) or lowest-ob­ served-adverse-effect levels (LOAELs) in animal or hu­ man studies. The most sensitive...

There are a growing number of studies documenting that, similarly to patients with solid cancers, also patients with hematological malignancies (i.e., acute leukemia, lymphoproliferative and myeloproliferative neoplasms and plasma cell disorders) are at increased risk of thrombosis. The pathogenesis of the hypercoagulable state associated with hematological cancers is often multifactorial. Cont...

Systemic lupus erythematosus (SLE) is the most common multisystem connective tissue disease. It is characterised by a wide variety of clinical features and presence of numerous auto-antibodies, circulating immune complexes and widespread immunologically determined tissue damage [1]. Hematological abnormalities are common in SLE. All the cellular elements of the blood & coagulation pathway can b...

BACKGROUND Molecular interrogation of genetic information has transformed our understanding of disease and is now routinely integrated into the workup and monitoring of hematological malignancies. In this article, a brief but comprehensive review is presented of state-of-the-art testing in hematological disease. METHODS The primary medical literature and standard textbooks in the field were q...

BACKGROUND Hematological markers of the systemic inflammatory response (SIR) including the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and the combination of NLR with PLR (CNP) are associated with prognosis of patients with esophageal squamous cell carcinoma (ESCC). However, their value in predicting the sensitivity to chemoradiotherapy in patients with ESCC is unc...

Background:Numerous studies have focused on the association of methionine synthase (MS) A2756G polymorphism and acute hematological cancer risk. However, the results remain inconsistent. Therefore, a meta-analysis was performed to derive a more precise estimate of the association between them. Methods: This meta-analysis involved 25 articles (26 studies) including 8641 hematological cancer pati...

Heat stress is one of the major limiting factors of production efficiency in the swine industry. The aims of the present study were 1) to observe if hemorheological and hematological parameters could be associated to physiological acclimation during the first days of heat stress exposure and 2) to determine if water restriction could modulate the effect of thermal heat stress on physiological, ...

conclusions the incidence of ipa in allogeneic hsct and patients with hematological malignancies was relatively high and a. flavus was the most common cause of pa. as molecular methods had higher sensitivity, it may be useful as screening methods in hsct and patients with hematological malignancies, or to determine when empirical antifungal therapy can be withheld. results seven (15.2%) out of ...