Non-penetrating injuries of the chest wall can give rise to a variety of cardiac lesions. The extent of cardiac damage depends on the intensity of the injury and on pre-existent disease of the heart. In the majority of cases there is a direct blow to the anterior chest wall but serious myocardial damage has been produced by blows directed against the posterior chest wall and abdomen. The crushi...

Inhibition of angiotensin II type 1 receptor (AT1R) is an important therapy in the management of hypertension, particularly in the immediate post-myocardial infarction period. Yet, the role of AT1R in the acute onset of myocardial ischemia and reperfusion injury still remains controversial. Thus, the present study determined the effects of chronic losartan treatment on heart ischemia and reperf...

An unusual case of a self-inflicted intracardiac injury with a sewing needle caused a pneumothorax. Fewer than ten cases of needles in the heart have been reported in the recent medical literature; none of these cases was associated with presence of a pneumothorax. The literature regarding self-inflicted injury with needles in the heart is reviewed.

this study briefly reviews the heart abnormalities in diverse intracranial pathologies, including strokes, spontaneous and traumatic subarachnoid hemorrhage and intracranial hemorrhage, and presents the results of a one-year prospective study of heart abnormalities in patients with moderate to severe head injuries and subarachnoid hemorrhage. different abnormalities such as: qt -interval, t -wa...

perhaps, due to the impact of post-traumatic stress disorder (ptsd) on biological markers of cardiovascular such as systolic and diastolic blood pressure, heart rate, body temperature, physiological response to reminders of trauma has become an essential part and hallmark of the diagnostic and statistical manual of mental disorders (fifth edition-dsm-5, american psychiatric association, 2013). ...

In Chagas disease, CD8(+) T-cells are critical for the control of Trypanosoma cruzi during acute infection. Conversely, CD8(+) T-cell accumulation in the myocardium during chronic infection may cause tissue injury leading to chronic chagasic cardiomyopathy (CCC). Here we explored the role of CD8(+) T-cells in T. cruzi-elicited heart injury in C57BL/6 mice infected with the Colombian strain. Car...

Myocardial injury is increased in the aged heart following ischemia-reperfusion (ISC-REP) compared to adult hearts. Intervention at REP with ischemic postconditioning decreases injury in the adult heart by attenuating mitochondrial driven cell injury. Unfortunately, postconditioning is ineffective in aged hearts. Blockade of electron transport at the onset of REP with the reversible inhibitor a...