BACKGROUND Orthotopic liver transplantation (OLT) is an effective treatment for fulminant hepatic failure (FHF), but postOLT mortality is higher for patients with FHF than for patients with other indications for OLT. In the current study, a large cohort of patients who underwent OLT for FHF was evaluated to develop and validate a system useful for estimating postOLT patient survival. METHODS ...

Fulminant hepatic failure (FHF) in humans produces a bleeding diathesis due in large part to a reduction in the biosynthesis of liver-derived coagulation factors. Remarkably, factor VIII procoagulant activity is elevated in most of these patients despite widespread liver cell death. FHF can be modeled in mice by administration of azoxymethane, the active ingredient found in cycad palm nuts. We ...

Fulminant hepatic failure (FHF) is a true medical emergency. It is a clinical syndrome characterized by the appearance of sudden marked impairment of liver cell function with hepatic encephalopathy, resulting from acute necrosis or dysfunction of a large portion of liver parenchyma. It is uncommon, but not rare. An estimated 2000 to 2500 deaths per year in the United States are due to FHF. Even...

This is the second of two articles on the effects of Old-Age Disability Insurance (OASDI) and Supplemental Security Income (SSI) payments on the poverty status of children. Based primarily on a data file from the 1990 SIPP matched with Social Security Administration (SSA) administrative records, the principal findings in the article are that: (1) the families of children who were entitled to su...

Fulminant hepatic failure (FHF) in association with metastatic cancer, without evidence of liver metastases, has not been previously reported in the literature. This report concerns a case of FHF in a 36-year-old man with advanced germ cell tumour arising from an extragonadal (retroperitoneal) primary. Liver function and encephalopathy improved following chemotherapy, suggesting prompt diagnosi...

The aftermath of the HIV and AIDS pandemic has resulted in great suffering in terms of loss of income, poor quality of life, morbidity and mortality, with children being destitute and orphaned at an alarming rapid rate. Families and communities are currently unable to cope with the effects of HIV and AIDS with special emphasis on the care and support of the affected orphans and vulnerable child...

This work is aimed at investigating the structural deterioration and frost heaving force evolution characteristics of flawed rocks using a self-developed (FHF) measurement system. Three kinds preflawed with different flaw geometry parameters were used to conduct FHF tests. The testing results reveal five distinguished stages from curve; they are inoculation stage, explosive decline steady recov...

Real-time detection of early chatter is a vital strategy to improve machining quality and material removal rate in the high-speed milling processes. This paper proposes maximum entropy (MaxEnt) feature-based reliability model method for real-time based on multiple sampling per revolution (MSPR) technique second-order (SORM). To enhance reliability, MSPR used acquire sets once-per-revolution sam...

PURPOSE There is a dearth of research on older adoptive parents caring for minor children, despite a growing number of such adoptions finalized each year. This study offers a large-scale investigation of adoptive families headed by older parents. We describe these families and explore how preadoptive kinship between the adoptive parent and the child impacts adoption outcomes. DESIGN AND METHO...