UNLABELLED BACKGROUND.: Microvascular free tissue transfer has become increasingly popular in the reconstruction of head and neck defects, but it also has its disadvantages. Tissue engineering allows the generation of neo-tissue for implantation, but these tissues are often avascular. We propose to combine tissue-engineering techniques together with flap prefabrication techniques to generate a ...

There is a growing interest in making relational DBMSs work synergistically with MapReduce systems. However, there are interesting technical challenges associated with figuring out the right balance between the use and co-deployment of these systems. This paper focuses on one specific aspect of this balance, namely how to leverage the superior indexing and query processing power of a relational...

The Hadoop Distributed File System (HDFS) is designed to store very large data sets reliably, and to stream those data sets at high bandwidth to user applications. In a large cluster, thousands of servers both host directly attached storage and execute user application tasks. By distributing storage and computation across many servers, the resource can grow with demand while remaining economica...

Abstract Extracellular matrix (ECM) proteins play a pivotal role in cell growth and differentiation. To characterize aged ECM proteins, we compared the proteomes by shotgun method of young (passage #15) late senescent #40) human dermal fibroblasts (HDFs) using SDS-PAGE coupled with LC–MS/MS. The relative abundance identified was determined mol% individual as semi-quantitative index. Fifteen inc...

The Hubble Deep Fields represent our best opportunity for probing galaxy evolution over a substantive look-back time. However as with any dataset the HDFs are prone to selection biases. These biases are extremely severe beyond z ∼ 1.25 such that a meaningful interpretation of generic galaxy evolution is not possible. We can however extract well defined volume-limited samples at z < 1. The data ...

Phenyl-2-pyridyl ketoxime (PPKO) was found to be one of the small molecules enriched in the extracellular matrix of near-senescent human diploid fibroblasts (HDFs). Treatment of young HDFs with PPKO reduced the viability of young HDFs in a dose- and time-dependent manner and resulted in senescence-associated β-galactosidase (SA-β-gal) staining and G2/M cell cycle arrest. In addition, the levels...