background: ß-carbolines, harmaline and harmine, are the major alkaloids presenting in the seeds of the peganum harmala l. these alkaloids are known as herbal active principals with potential use in pharmaceutical and medicine. objectives: to assess the growth inhibitory effect of phyto-alkaloids, harmaline and harmine, on cancer cell lines. methods: the p. harmala l.’s alkaloids were extracted...

based on the extensive application of peganum harmala (p.h) seeds in the asian traditional medicine, we tried to investigate its possible anxiety effect. method: the effect of p.h. extract inhalation was evaluated in adult male rats using elevated plus-maze apparatus. the humidity of prepared ethanol extract was 37%. animals in different groups (n=6) received 2, 4, 6, 12 or 18 gr/ml doses of th...

This study represents the extraction of keratin from hedgehogs spines doped with Harmaline and Ginkgo Biloba, electrospun on surface cotton fabric (animal rights laws were performed). The field emission scanning electron microscopy (FESEM) was used to investigate morphology produced Biloba (KHG). thermogravimetric analysis (TGA) shows weight loss samples in different temperatures. aim goal prod...

Objective: The present study was conducted to investigate antibacterial properties of fruit and flower of Peganum harmala. Material and Methods: Column chromatography, followed by preparative thin layer chromatography (TLC) was used for final purification. The structure of pure alkaloids was determined using spectroscopic methods (1H-N...

Ibogaine, an indole alkaloid that causes hallucinations, tremor, and ataxia, produces cerebellar neurotoxicity in rats, manifested by degeneration of Purkinje cells aligned in narrow parasagittal bands that are coextensive with activated glial cells. Harmaline, a closely related alkaloid that excites inferior olivary neurons, causes the same pattern of Purkinje cell degeneration, providing a cl...