OBJECTIVE The Hospital Anxiety and Depression Scale (HADS) is widely used to screen for anxiety and depression. A large literature is citable in support of its validity, but difficulties are increasingly being identified, such as inexplicably discrepant optimal cutpoints and inconsistent factor-structures. This article examines whether these problems could be due to the construction of the HADS...

Cosco and colleagues [this issue] provide a well done and transparently reported systematic review of the Hospital and Anxiety Depression Scale (HADS) literature of the past decade. They conclude that the underlying structure of the HADS is inconsistent across samples and highly dependent on the statistical methods used to establish that structure. The implication is that the HADS is not a depe...

OBJECTIVES To assess the role of brain networks in emotion regulation and post-traumatic complaints in the sub-acute phase after non-complicated mild traumatic brain injury (mTBI). EXPERIMENTAL DESIGN Fifty-four patients with mTBI (34 with and 20 without complaints) and 20 healthy controls (group-matched for age, sex, education, and handedness) were included. Resting-state fMRI was performed ...

BACKGROUND The impaired decision-making with high risk-aversive behavior and elevated impulsivity are reported as a trait feature in anxiety disorders including panic disorder (PD). It is hypothesised that PD patients exhibit difficulties in executive functions which can influence patients behavioural strategies e.g. problem solving, decision making, planning, impulse control. The aim of this s...

OBJECTIVE Both depression and anxiety have been associated with poor prognosis in patients with acute coronary syndrome (ACS). However, certain symptoms and how they are measured may be more important than others. We investigated three different scales to determine their predictive validity. METHODS Patients with ACS (N = 598) completed either the Hospital Anxiety and Depression Scales (HADS-...

BACKGROUND The presence of depression symptomatology significantly deteriorates the prognosis for the patient. There are many instruments developed to measure depression and anxiety in clinical trials; however, the suitability of the specific scale for screening these disorders in cardiovascular patients is debatable. The aim of current study is to verify which of the major assessment instrumen...

OBJECTIVE To systematically review the latent structure of the Hospital Anxiety and Depression Scale (HADS). METHODS A systematic review of the literature was conducted across Medline, ISI Web of Knowledge, CINAHL, PsycInfo and EmBase databases spanning articles published between May 2000 and May 2010. Studies conducting latent variable analysis of the HADS were included. RESULTS Twenty-fiv...

BACKGROUND Because the primary aim of infertility treatment is to achieve pregnancy, mental health care during this treatment is often neglected. However, the inability to conceive children is stressful for couples throughout the world. Thus, the purpose of this study was to investigate factors related to the anxiety and depression of female infertility patients. METHODS Participants included...

OBJECTIVE To evaluate the short- and long-term effects of aerobic interval training on quality of life and on symptoms of anxiety and depression among patients with ischaemic heart failure and an implantable cardioverter defibrillator. DESIGN Prospective, non-randomized controlled study. SUBJECTS Patients with ischaemic heart failure and an implantable cardioverter defibrillator, willing to...

BACKGROUND Evidence on the long-term usefulness of anti-depressants in managing depression in cardiometabolic disease is limited. AIM We examined the effects of anti-depressant prescribing on depressive symptoms at 12 months follow-up in patients with cardiometabolic disease and a positive depression screening result at baseline. DESIGN AND SETTING We retrospectively reviewed routine UK pri...