Oral drug delivery system has been area of interest for researcher and scientist to explore it to the extreme potential in drug delivery system in past few years. The researchers are focusing on this drug delivery because of ease of administration and comfort offered by this route to patient. Hence drug delivery can be achieved by incorporating medicament in Chewing gum (CG) base because oral m...

Streptococcus mutans is strongly associated with caries in humans1 and its level in the mouth can be a good indicator of caries-risk. However, caries is a multifactorial disease and the presence of high levels of Streptococcus mutans at a particular site does not imply that such a site will inevitably develop a lesion. In addition, Streptococcus mutans is not found alone in association with car...

Background and Aim: Pain control is important for both patients and clinicians in orthodontics. The researchers have used different modalities for this purpose, each having its own advantages and disadvantages. The aim of this study was to compare the efficacy of ketoprofen gum and gel for pain relief after activation of fixed ortho-dontic appliances. Materials and Methods: In this double-bl...

INTRODUCTION The aim of this study was to compare the efficacy of ibuprofen, viscoelastic bite wafers, and chewing gum in reducing orthodontic pain. METHODS This randomized clinical trial included 50 girls between the ages of 13 and 18 years classified into 5 groups of 10 each: placebo, ibuprofen (400 mg), chewing gum, soft viscoelastic wafer, and hard viscoelastic wafer. The patients in each...

PURPOSE The present study was carried out to identify how gum chewing with and without occlusal support by implant prostheses affects brain function as well as chewing function. METHODS Twenty-four subjects rehabilitated with implant-supported fixed prostheses were evaluated. An electroencephalograph (EEG) (ESA-Pro) and mandibular kinesiograph (Bio PAK(®)) wear used to measure brain function ...

To compare the efficacy of simo decoction (SMD) combined with acupuncture at the tsusanli acupoint or chewing gum alone for treating postoperative ileus in patients with hepatocellular carcinoma (HCC) after hepatectomy.In postoperative ileus, a frequent complication following hepatectomy, bowel function recovery is delayed, which increases length of hospital stay. Studies suggest that chewing g...

BACKGROUND Chewing gum may enhance intestinal motility after surgery. This trial studied whether chewing gum could lead to a further reduction in ileus in patients who had a laparoscopic colorectal resection and followed an enhanced recovery programme. METHODS Patients undergoing laparoscopic colorectal resection were randomized to a control or intervention group. Patients in the control grou...

OBJECTIVE The aim of this study was to systematically review the current literature on the clinical effects of sugar-free chewing gum on plaque indices and parameters of gingival inflammation. MATERIAL AND METHODS The MEDLINE-PubMed, Cochrane-CENTRAL and EMBASE databases were searched up to 20 April 2012 to identify any appropriate studies. Plaque indices and parameters of gingival inflammati...

In present era, many research and technological advancements are made in the field of oral drug delivery as it is highly accepted amongst patients.. Chewing gum is one of the very popular oral confectionery products. Medicated chewing gums are prepared by using a water insoluble gum base, elastomers, emulsifiers, fillers, waxes, antioxidants, softeners, sweeteners, food colourings, flavoring ag...