the stimulatory effect of the extract of portulaca oleracea (p. olerace) on β-adrenoceptor of tracheal smooth muscle was examined. to examine β-adrenoceptor stimulatory effect, concentration response curve to isoprenaline was obtained in pre-contracted tracheal smooth muscle in the presence of three concentrations of aqueous-ethanolic extract, propranolol and saline. values of ec50 (the effecti...

background cellular level of enzyme activity can serve as a reliable biomarker in the event of environmental/chemical insults. objectives the present study investigated time-dependent alterations of erythrocyte glutathione s-transferase (ery-gst) activity of non-malarious guinea pigs (cavia tschudii) administered with pyrimethamine/sulfadoxine and artemether/lumefantrine combination therapies. ...

BACKGROUND Allergic sensitization and reactions to guinea pig (Cavia porcellus) have been well documented in laboratory animal handlers, primarily manifesting as rhinitis, conjunctivitis, and asthma. Severe allergic reactions, however, are rare. METHODS We report two patients with severe allergic reactions following non-occupational exposure to guinea pigs. The first patient, an 11-year-old f...

We have examined the capacity of a live avirulent mutant form of the intracellular bacterial pathogen Legionella pneumophila to induce immune responses and protective immunity in guinea pigs. The mutant L. pneumophila is nonlethal to guinea pigs and does not revert to virulence with passage through guinea pigs. In contrast, exposure of guinea pigs to aerosols containing wild-type L. pneumophila...

Osteoarthritis is a joint disease involved in articular cartilage, subchondral bone, meniscus and synovial membrane. This study sought to examine cartilage degeneration, subchondral bone mineral density (BMD) and meniscal mineral density (MD) in male Hartley, female Hartley and female strain 13 guinea pigs to determine the association of cartilage degeneration with subchondral BMD and meniscal ...

objective(s): the effect of the extract of crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined.   materials and methods: ovalbumin (oa) sensitized guinea pigs were given drinking water alone (group s), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6...

the current study intends to analyze the effects of methionine on the ovulation of guinea pigs. 60 guinea pigs were given 4 different treatments in a completely randomize design. the treatments contained 0, 2, 4 and 6 percent of methionine per kg as fed. after two weeks as adaptation period, the four different treatments were given to the animals for two estrus cycle. after synchronization whic...

objective: the use of drugs with herbal origin is increasing for treatment of gastrointestinal (gi) disorders. rosa damascena (r. damascena) is a well-known plant suggested to have beneficial effect on gi system. in this study, the effect of aqueous fraction of r. damascena on the contractionsofisolated guinea pig ileum was investigated. materials and methods: aqueous fraction of plant was obta...

our  previous  studies demonstrated  the  preventive effect  of  nigella  sativa  extract  on asthma and water-soluble substances of this extract, especially its methanol fraction were responsible for this relaxation on contracted tracheal chains of guinea pigs. for the first time, the present study has been conducted to determine the main constituents of its methanolic extract. four constituen...

The geocorine (Hemiptera: Heteroptera: Lygaeoidea: Geocoridae) true bug genus Umbrageocoris Kóbor, 2019 is redefined based on new morphological information from newly acquired specimens. Two species are described: U. boonei sp. nov. continental Indomalaya and malipatili Australia; two combinations proposed: elegantulus (Distant, 1904), comb. , woodwardi (Malipatil, 1994), (both transferred Geoc...