BACKGROUND: The present study focuses on the design and evaluation of colon targeted matrix tablets of Mebeverine hydrochloride using natural gums like guar gum, xanthan gum at different concentrations. This novel approach is expected to be promising drug delivery system for delivering Mebeverine HCl to the colon for its local action and thereby minimizing systemic side effects of the drug. MET...

Sustained release tablets of isoniazid were fabricated using guar gum and carbapol, Tragacanth Gum and PEG-6000, in different proportion and combinations by direct compression technique, Bulk density, tapped density, compressibility index, Hausner ratio before being punched as tablets. The tablets were evaluated for physical characteristic like hardness, weight variation, friability, and drug c...

Mucilage of malva nut fruit has been used as traditional medicine in Thailand. Our laboratory has succeeded in extracting malva nut gum (MNG) from malva nut seeds by using alkaline-extraction method. The extract had higher gelling properties compared to water-extracted MNG. This research was aimed to investigate the effect of MNG on the retardation of glucose diffusion in in vitro dialysis proc...

guar gum and whey proteins concentrate (wpc-35) were used as functional additives to improve the functional characteristics (hardness and meltability) of the na-caseinate-based imitation cheese. also, the alterations in the composition, sensory acceptance, color, and texture caused by these ingredients were evaluated. imitation cheeses were formulated with three levels each of wpc (0, 1.5, and ...

The effect of prolonged consumption of guar gum on iron absorption and Fe status was investigated in rats. Experiments with closed loops of duodenum, isolated in situ, were designed to reveal changes in the short-term regulation of duodenal Fe uptake, induced by challenge with low- and high-Fe meals. In separate experiments, the effect of guar gum on the capacity of intact rats to maintain Fe s...

Six healthy non-obese male subjects were given three test meals containing 100 g carbohydrate and 1.5 g soluble paracetamol, supplemented on one occasion with 10 g guar gum and on another with 10 g sugarbeet fiber. A further six subjects were given the same test meal supplemented on one occasion with 10 g soya-bean-cotyledon fibre and on another, 5 g glucomannan. Venous blood samples were taken...

the aim of this work was to optimize the coagulation-flocculation (cf) process applied tomunicipal wastewaters (ww). optimization of cf was performed to minimize chemical oxygen demand(cod), turbidity, sludge produced, and some metals in sludge. a box-behnken design was used to evaluate the effects and interactions of three factors such as type of biopolymer (guar, mesquite seed gum and opuntia...

introduction: cakes are usually formulated including wheat flour, sugar, egg and some liquids such as milk, water and oil. the textural properties of gluten in dough such as tensile, expansion and tolerance capability during mixing are major factors in baking industry. in fact, the structural protein to produce bread, cakes, muffins and biscuits is called gluten and the absence of gluten due to...

BACKGROUND Guar galactomannan is a plant polysaccharide with extensive applications in food, paper, textile and petroleum industries. The main advantages for using guar are its low cost, easy availability and capacity to form viscous solutions and gels at low concentration. Additionally, chain architecture of guar galactomannan can be selectively modified to tailor properties of guar formulatio...