نتایج جستجو برای: granulocyte colony

تعداد نتایج: 64612  

Journal: :The Journal of Experimental Medicine 1990
Jonathan L. McQualter Rima Darwiche Christine Ewing Manabu Onuki Thomas W. Kay John A. Hamilton Hugh H. Reid Claude C.A. Bernard

Experimental autoimmune encephalomyelitis (EAE), a model for multiple sclerosis, can be induced by immunization with a number of myelin antigens. In particular, myelin oligodendrocyte glycoprotein, a central nervous system (CNS)-specific antigen expressed on the myelin surface, is able to induce a paralytic MS-like disease with extensive CNS inflammation and demyelination in several strains of ...

Journal: :The Journal of biological chemistry 2001
B Bishop D C Koay A C Sartorelli L Regan

Granulocyte colony-stimulating factor is a long-chain cytokine that has both biological and therapeutic applications. It is involved in the production and maturation of neutrophilic progenitor cells and neutrophils and is administered to stimulate the production of white blood cells to reduce the risk of serious infection in immunocompromised patients. We have reengineered granulocyte colony-st...

2013
H. P. Koeffler

We show that 1,25-dihydroxyvitamin D3 (1,25[0H12D3), the most hormonally active metabolite of vitamin 113, modulates sensitively and specifically both the protein and messenger RNA accumulation of the multilineage growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF). The regulation of GMCSF expression is seen in both normal human mitogen-activated T lymphocytes and T lymphocy...

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