discussed, and he points out that merely because a disease is found to be familial in incidence does not mean it is hereditarily transmitted; leprosy, for instance, was long held to be a hereditary disease, and a law was actually proposed in the Norwegian Parliament forbidding the marriage of lepers for that reason. It was only with the discovery of the leprosy bacillus by Hansen that the true ...

Graft-vs-host disease is still the leading cause of morbidity and mortality in patients undergoing bone marrow transplantation. It is important to start treatment early to reduce the severity and consequences of this complication. Cutaneous lesions are often the presenting compliant of graft-vs-host disease and presage visceral involvement. We present the case of a 45-year-old woman with multip...

* This project is supported by the NSERC of Canada. Abstract An all-new model of the multicast communication is presented in this paper. It utilizes the architecture of the Host Identity Protocol (HIP), which is being defined by the IETF, and two levels of hierarchical administration to achieve secure authentication of the identity of the group members and administration based on the ISP. It is...

Nod-like receptors have emerged as an important family of sensors in host defense. These receptors are expressed in macrophages, dendritic cells and monocytes and play an important role in microbial immunity. Some Nod-like receptors form the inflammasome, a protein complex that activates caspase-1 in response to several stimuli. Caspase-1 activation leads to processing and secretion of pro-infl...

(1844 articles) Transplantation • (4939 articles) Immunobiology • Articles on similar topics can be found in the following Blood collections http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#repub_requests Information about reproducing this article in parts or in its entirety may be found online at: http://bloodjournal.hematologylibrary.org/site/misc/rights.xhtml#reprints Infor...

Extracorporeal photopheresis (ECP) is an immunomodulatory therapy which has been used in the treatment of chronic GVHD (cGVHD). ECP involves separation of the mononuclear cells with leukapheresis, followed by ex vivo administration of 8-methoxypsoralen and UV-A radiation and reinfusion to the patient. Aim of the study was to evaluate clinical and immunomodulatory effect of ECP procedures in pat...