BACKGROUND The internal mammary artery (IMA) is the preferred conduit for bypassing the left anterior descending (LAD) artery in patients undergoing coronary artery bypass grafting. Systematic evaluation of the frequency and predictors of IMA failure and long-term outcomes is lacking. METHODS AND RESULTS The Project of Ex-vivo Vein Graft Engineering via Transfection (PREVENT) IV trial partici...

BACKGROUND Proenkephalin (pro-ENK), a stable and reliable surrogate marker for unstable enkephalins, was found to be associated with acute kidney injury and chronic renal failure in previous studies. We aimed to investigate whether pro-ENK is linked to chronic kidney injury and poor long-term outcome in renal transplant recipients (RTR). METHODS We included 664 stable RTR and 95 healthy kidne...

purposes: to report a case of primary graft failure (pgf) and systemic manifestations of herpes simplex virus (hsv) infection following transplantation of an hsv-contaminated donor cornea. patient and findings: a 28-year-old male with history of penetrating keratoplasty 12 days before, developed intraocular inflammation with marked anterior chamber reaction, graft edema and elevated intraocular...

BACKGROUND The aim of the present study was to assess the long-term graft patency rate of the radial artery (RA), in comparison to the saphenous vein (SV) in patients harvested for both vessels. METHODS AND RESULTS RA and SV were concomitantly used for coronary artery bypass grafting in 318 patients in an 8-year period from January 2002 to March 2010. During follow-up, graft patency was asses...

Artery reconstruction in upper extremities is rare performed compared to artery reconstruction in lower extremities. Primary vascular repair was performed in many cases. An interposition vein graft or venous bypass grafting were applied in order to alleviate thrombus in blood vessel. However, one or more of the applied vein graft are blocked or severely narrowed due to the mismatched internal d...

BACKGROUND AND OBJECTIVES The influence of pretransplant dialysis modality on post-transplant outcomes is not clear. This study examined associations of pretransplant dialysis modality with post-transplant outcomes in a large national cohort of kidney transplant recipients. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Linking the 5-year patient data of a large dialysis organization to the Sc...

BACKGROUND Little research has explored pre-transplantation psychological factors as predictors of outcome after liver or kidney transplantation. Our objective is to determine whether report of depressive symptoms on waiting list predicts outcome of liver and kidney transplantation. METHODS Patients on waiting list for liver or kidney transplantation were classified for report or non-report o...

The decision to accept or decline a liver allograft for a patient on the transplant waiting list is complex. We hypothesized that surgeons are not accurate at predicting donor-specific risks. Surgeon members of the American Society of Transplant Surgeons were invited to complete a survey in which they predicted the 3-year risk of graft failure for a 53-year-old man with alcoholic cirrhosis and ...

OBJECTIVES To determine the prevalence of hypoalbuminemia in children listed for renal transplantation and to evaluate the effect of pretransplant hypoalbuminemia on posttransplant outcomes. STUDY DESIGN Retrospective cohort analysis of children receiving their first kidney transplant in the US between January 2000 and December 2010 obtained through the Organ Procurement and Transplantation N...

We investigated the effect and outcome of allogeneic peripheral blood stem cell (PBSC) rescue for aplastic anemia (AA) patients with graft failure after allogeneic bone marrow transplantation (BMT). Seven (28%) of 25 AA patients who received BMT from HLA-identical sibling donors developed late graft failure at a median of 7 months (range, 2.0-9.3 months) after transplantation. The patients with...