A randomized block experiment conducted on Sultanpur silt loam evaluated the N effects on growth and nitrate accumulation of okra (Hibiscus esculents L. cv. Sabz pari) and carrot (Daucus carota L. cv. T29). Treatments consisted of a control, 100, 150 and 200 kg N ha. Significantly higher yields of carrot and okra were recorded at 150 kg N ha. Nitrate concentration in both increased (> 35 to 200...

Objective(s): In the present study,a new series of 6-methoxy-2-arylquinoline analogues was designed and synthesized as P-glycoprotein (P-gp) inhibitors using quinine and flavones as the lead compounds. Materials and Methods: The cytotoxic activity of the synthesized compounds was evaluated against two human cancer cell lines including EPG85-257RDB, multidrug-resistant gastric carcinoma cells (P...

BACKGROUND Fever is the most common reason for a child to be taken to a general practitioner (GP), especially during out-of-hours care. It is mostly caused by self-limiting infections. However, antibiotic prescription rates remain high, especially during out-of-hours care. Anxiety and lack of knowledge among parents, and perceived pressure to prescribe antibiotics amongst GPs, are important det...

Based on fuzzy gp*-closed sets and gp*-open sets, in this paper we have introduced gp*- neighborhoods, gp*-Interior gp*-Closure. Also investigated some of their elementary properties discuss important theorems

Many complex phenomena are difficult to investigate directly through controlled experiments. Instead, computer simulation is becoming a commonplace alternative to providing insight into such phenomena. The drive towards higher fidelity simulation continues to tax the fastest of computers, even in highly distributed computing environments. Computational fluid dynamics simulations in which fluid ...

Abstract We have updated and applied a convolutional neural network (CNN) machine-learning model to discover characterize damped Ly α systems (DLAs) based on Dark Energy Spectroscopic Instrument (DESI) mock spectra. optimized the training process constructed CNN that yields DLA classification accuracy above 99% for spectra signal-to-noise ratios (S/N) 5 per pixel. The is rate of correct classif...

p-glycoprotein (p-gp) is a trans-membrane drug efflux pump. several drugs are p-gp substrates. some drugs may affect the activity of p-gp by inhibiting its function, resulting in significant drug-drug interactions (ddis). it is critical to understand which drugs are inhibitors of p-gp so that adverse ddis can be minimized or avoided. this study investigated the effects of gliclazide, metformin,...

The present research was planned to explore the biochemical properties and antioxidant activity of newly developed Pakistani rye variants. For this purpose, four different variants (Gp-1, Gp-2, Gp-3, Gp-4) were procured from forage section Ayub Agriculture Research Institute, Faisalabad. In first phase, each sample milled convert it into powder analyzed for their phytochemical profile. second m...