Metronidazole and it’s derivatives are drugs that have both antiprotozoal and anti bacterial effect.The reproductive toxicity of metronidazole has been shown in some studies. To investigate the effect of metronidazole on spermatogenesis in adult male rats, this study was designed. Eighteen wistar male rats (70-90days old) were randomly divided into three groups. Animals in group I (Control grou...

Background: To study the effectiveness of Clomiphene citrate (CC) in preventing a premature LH surge during controlled ovarian stimulation in women undergoing assisted reproduction. Materials and Methods: Couples were randomized to receive human menopausal gonadotrophins (hMG) followed by CC or hMG alone till the day of hCG. The primary outcomes were the incidence of a clinical pregnancy and pr...

428 receptors than the myometrium4. However, in younger women, besides its agonist action, these drugs may also block the estrogen receptors in the hypothalamus leading to intense output of gonadotrophins which lead to ovarian stimulation and growth of myoma. An increase in cervical and endometrial polyps with neoplastic change in the endometrium has been reported. The potential for similar pro...