نتایج جستجو برای: glycosyltransferase
تعداد نتایج: 2654 فیلتر نتایج به سال:
Golgi apparatus fractions from rat liver contained all glycosyltransferases which catalyze the in vitro biosynthesis of N-acetylneuraminylgalactosylglucosylceramide (G&, (Nacetylneuraminyl)2-galactosylglucosylceramide (GD3), N-acetylgalactosaminyl(Nacetylneuraminyl) galactosylglucosylceramide (GMz), galactosyl-N-acetylgalactosaminyl-(N-acetylneuraminyl)-galactosylglucosylceramide (GM& and Nacet...
MOTIVATION The emerging field of Glycomics requires the development of systems-based modeling strategies to relate glycosyltransferase gene expression and enzyme activity with carbohydrate structure and function. RESULTS We describe the application of object oriented programming concepts to define glycans, enzymes, reactions, pathways and compartments for modeling cellular glycosylation react...
Glycosyltransferases in the Golgi apparatus synthesize cell wall polysaccharides and elaborate the complex glycans of glycoproteins. To investigate the targeting of this type of enzyme to plant Golgi compartments, we generated transgenic Arabidopsis plants expressing alpha-2,6-sialyltransferase, a glycosyltransferase of the mammalian trans-Golgi cisternae and the trans-Golgi network. Biochemica...
Ansamitocins are potent antitumor maytansinoids produced by Actinosynnema pretiosum. Their biosynthesis involves the initial assembly of a macrolactam polyketide, followed by a series of postpolyketide synthase (PKS) modifications. Three ansamitocin glycosides were isolated from A. pretiosum and fully characterized structurally as novel ansamitocin derivatives, carrying a beta-D-glucosyl group ...
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