Skin absorption of glyceryl trinitrate (GTN) has been recognized for a long time. The effect of GTN and a placebo ointment in prevention of chest pain has been assessed and compared by studying the exercise capacity in 17 patients with angina pectoris. The placebo cream was ineffective but the GTN ointment was found to have beneficial effect in relief of pain in 16 cases. This was established b...

their interest in our article. First, we would like to apologize for mis-attributing the statement to the authors. The correct reference in our article was to 11 not 1 and it is not a direct quotation. We believe our survey provides sufficient evidence to raise concerns over the use of transtracheal ventilation using a high pressure source without control of airway pressure, but a survey lackin...

context hemorrhoidal disease is the most common anorectal disorder that requires surgical intervention. hemorrhoids require treatment when they result in symptoms such as bleeding or prolapse. surgical intervention is indicated for significant prolapse, and a number of accepted and viable methods are available for treating prolapsing hemorrhoids that do not reduce spontaneously (grade iii and i...

Coronary vasodilating activity of chromone derivatives has been reported.2) It is worth examining if chromanone derivatives have a coronary vasodilating effect, since they are chemically related to chromone. In the present study the effects of some benzylidene chromanones and its related compounds on coronary blood flow and myocardial oxygen consumption in anesthetized dogs and also on the oxyg...

Amlodipine significantly reduced both weekly anginal attack rate and consumption of glyceryl trinitrate tablets in patients with severe coronary artery disease. Exercise tolerance also significantly improved, with a 79% increase in the exercise time to onset of angina and a 59% decrease in ST-segment depression. Blood pressure was decreased, with no significant change in heart rate. No serious ...