Background The glycated hemoglobin (HbA1C) test, essential for diabetic patients follow-up, measures the concentrations of glycated hemoglobin in the blood, which can indicate, as they increase in proportion to glucose rates, the possibility of complications of the disease. Furthermore, the test points to the risk of Type 2 diabetes mellitus (T2D) development, for concentration values between 5...

Two techniques originally developed for measurement of glycated ("glycosylated") hemoglobin but also applicable to determination of glycated albumin are the thiobarbituric acid colorimetric technique (I) and the aminophenylboronic acid affinity chromatographic procedure (II). The latter reliably distinguishes diabetics from nondiabetics, and concentrations of glycated hemoglobin and glycated al...

Sodium–glucose co transporter 2 (SGLT2) inhibitors decrease glycated hemoglobin levels and have shown favorable effects on kidney cardiovascular outcomes in large clinical trials involving patients with type diabetes. This hemodynamic effect may also preserve function persons diseases due to causes other than

We present the first demonstration of glycated albumin detection and quantification using Raman spectroscopy without the addition of reagents. Glycated albumin is an important marker for monitoring the long-term glycemic history of diabetics, especially as its concentrations, in contrast to glycated hemoglobin levels, are unaffected by changes in erythrocyte life times. Clinically, glycated alb...