نتایج جستجو برای: glutathione peroxidase gshpx

تعداد نتایج: 63181  

Journal: :Atlas of Genetics and Cytogenetics in Oncology and Haematology 2017

Journal: :European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies 1994
R Schiavon G C Guidi S Biasioli E De Fanti L Targa

The kidney is a major source of the plasma enzyme glutathione peroxidase. We measured plasma glutathione peroxidase activity in 130 patients affected with different renal diseases at various stages, and compared it with the following indices of kidney function: serum creatinine, creatinine clearance, and urinary excretion of alpha 1-microglobulin, beta 2-microglobulin, albumin and N-acetyl-beta...

Journal: :The British journal of nutrition 2002
Robin Ornsrud Mette Lorentzen

The bioavailability of Se from raw and cured selenomethionine-enriched (Se-enriched) salmon fillets was assessed in Se-deficient male albino rats (Mol: Wist). A low-Se Torula yeast feed was supplemented with 0, 50, 100, 150 or 200 microg Se/kg as sodium selenite or as Se from raw or cured Se-enriched salmon. The diets were fed to weanling rats for 10 and 30 d. Bioavailability of Se was assessed...

Journal: :Environmental Health Perspectives 1998
Y S Ho J L Magnenat M Gargano J Cao

Reactive oxygen species (ROS) have been implicated in the pathogenesis of many clinical disorders such as adult respiratory distress syndrome, ischemia-reperfusion injury, atherosclerosis, neurodegenerative diseases, and cancer. Genetically engineered animal models have been used as a tool for understanding the function of various antioxidant enzymes in cellular defense mechanisms against vario...

2011
Levent Ediz Ozcan Hiz Halil Ozkol Elif Gulcu Murat Toprak Mehmet Fethi Ceylan

OBJECTIVE/AIM A new group of autoantibodies in Rheumatoid Arthritis (RA), the anti-cyclic citrullinated peptide (anti-CCP) antibodies directed to citrulline-containing proteins, which are of value for the severity of RA. Up to date, the relationship between anti-CCP antibodies and oxidant, anti-oxidant activity in patients with RA has not been elucidated in the previous studies. In this study w...

Journal: :The New England journal of medicine 2003
Stefan Blankenberg Hans J Rupprecht Christoph Bickel Michael Torzewski Gerd Hafner Laurence Tiret Marek Smieja François Cambien Jürgen Meyer Karl J Lackner

BACKGROUND Cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the control of reactive oxygen species. In vitro data and studies in animal models suggest that these enzymes may protect against atherosclerosis, but little is known about their relevance to human disease. METHODS We conducted a prospective study among 636 patients with su...

Journal: :Applied sciences 2021

The chronic effect of environmental methomyl on the antioxidant system in testis Nile tilapia (Oreochromis niloticus) and its recovery pattern was investigated. Tilapia were exposed to sublethal concentrations 0.2, 2, 20 200 ?gL?1 for 30 days thereafter moved methomyl-free water 18 days. Antioxidant levels testis, including glutathione peroxidase, catalase, glutathione-S-transferase, reductase,...

Journal: :Journal of the American College of Cardiology 1998
M Keith A Geranmayegan M J Sole R Kurian A Robinson A S Omran K N Jeejeebhoy

OBJECTIVES We sought to study the markers of lipid peroxidation and defenses against oxidative stress in patients with varying degrees of heart failure. BACKGROUND Despite advances in other areas of cardiovascular disease, the morbidity and mortality from congestive heart failure (CHF) are increasing. Data mainly from animal models suggest that free radical injury may promote myocardial decom...

Journal: :nephro-urology monthly 0
omid sedighi department of nephrology, faculty of medicine, imam khomeini hospital, mazandaran university of medical sciences, sari, ir iran atieh makhlough diabetes research center, faculty of medicine, imam khomeini hospital, mazandaran university of medical sciences, sari, ir iran; diabetes research center, faculty of medicine, imam khomeini hospital, mazandaran university of medical sciences, sari, ir iran. tel: +98-9111510564 mohammad shokrzadeh pharmaceutical sciences research center, department of toxicology and pharmacology, faculty of pharmacy, mazandaran university of medical sciences, sari, ir iran shiva hoorshad imam khomeini hospital, mazandaran university of medical sciences, sari, ir iran

conclusions plasma se and gpx levels were lower in type two diabetic patients with macroalbuminuria and related to the stage of diabetic nephropathy. results plasma se and gpx concentrations were significantly lower in diabetic patients with macroalbuminuria than other study groups (p < 0.001). albuminuria (alb/cr in random urine sample) had a negative correlation with plasma se (r = -0.40, p =...

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