the aim of this study was to investigate the effects of ethanolic extract of the whole plant of phyllanthus rheedii wight p.rheedii as antihyperglycemic, antihyperlipidemic and antioxidant effect in streptozotocin (stz) induced diabetic rats. male wistar rats were administered p.rheedii (250 mg/kg) orally for 21 days and blood glucose level was measured weekly. at the end of 21 days, the serum ...

this study was designed to explore the protective effects of abrus precatorius l. (leguminosae) (ap) in hepg2 cells and n-nitrosodiethylamine (ndea) induced hepatocellular carcinoma in swiss albino rats. the effects of aqueous/ethanolic (50%) extract of ap on hepatic markers, haematological and histopathological parameters, and antioxidant enzymes were evaluated in ndea (200 mg/kg and ccl4, 3 m...

background : studies show that there is association between air pollution and disturbances on normal function of various systems of body. the main aim of this study was to determine the effects of diesel oil vapor inhalation on serum creatine, alkaline phosphatase, sgot and sgpt levels as indices of liver function in male rats. methods: thirty two rats were randomly divided into 4 groups: contr...

abstract objective: thyroid dysfunction complicates the metabolic derangement observed in diabetes mellitus (dm). it is necessary to recognize and treat it, when present, in order to achieve stability of metabolic control in these patients. the aim of this study was to investigate the effect of dm on thyroid hormone levels and other biochemical variables. materials and methods: to determine the...

A novel beta-transaminase gene was cloned from Mesorhizobium sp. strain LUK. By using N-terminal sequence and an internal protein sequence, a digoxigenin-labeled probe was made for nonradioactive hybridization, and a 2.5-kb gene fragment was obtained by colony hybridization of a cosmid library. Through Southern blotting and sequence analysis of the selected cosmid clone, the structural gene of ...

1. Clostridium pasteurianum was grown on a synthetic medium with the following carbon sources: (a) (14)C-labelled glucose, alone or with unlabelled aspartate or glutamate, or (b) unlabelled glucose plus (14)C-labelled aspartate, glutamate, threonine, serine or glycine. The incorporation of (14)C into the amino acids of the cell protein was examined. 2. In both series of experiments carbon from ...

Difluoro-oxaloacetate interacts with the aldimine form of aspartate transaminase to give a complex, the dissociation constant ofwhich has been determined spectrophotometrically and by 19F n.m.r. (nuclear magnetic resonance). The 19F n.m.r. line-width-pH and chemical-shift-pH profiles of difluoro-oxaloacetate in the presence of the aldimine form of the enzyme both show inflexion points in the pH...