Impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) represent intermediate states between normal fasting glucose (NFG) or normal glucose tolerance (NGT), respectively, and diabetes (1). The regulation of fasting and glucose concentrations after an oral glucose load is dependent on different physiological mechanisms (2), and current evidence suggests that IFG and IGT have differe...

the diabetes is an autoimmune disease, in which the role of autoantibodies is of a specific importance. the appearance of these autoantibodies can be the first symptom in the serum of type i diabetic patients, which may appear ten years before onset of the disease. the most important autoantibodies include glutamic acid decarboxylase autoantibodies (gad65-ab). this can be used as a good tool fo...

Background: Chest X-ray is one of the examinations required for an annual health checkup. The interaction of radiation to the medium produces free radicals, which consequently causes biological changes either structural or properties of the cells. Whether the radiation from Chest X-ray upright technique affects the plasma membrane fluidity of thalassemic red blood cells (RBCs) is still unclear....

T here has been no consensus for screening methodology, diagnosis, and management of gestational diabetes mellitus (GDM). We aimed to evaluate routine practice for GDM management across the U.K., including postnatal care. Questionnaires were sent to all members of the Association of British Clinical Diabe-tologists. They were asked to describe how patients were screened for GDM, the diagnostic ...

OBJECTIVE We evaluated various strategies to identify individuals aged 45-74 years with pre-diabetes (either impaired glucose tolerance or impaired fasting glucose). RESEARCH DESIGN AND METHODS We conducted a cost analysis to evaluate the effectiveness (proportion of cases identified), total costs, and efficiency (cost per case identified) of five detection strategies: an oral glucose toleran...

OBJECTIVE Since 1997, the American Diabetes Association has recommended that nondiabetic individuals >/=45 years of age be screened for diabetes at least every 3 years. We sought to characterize the frequency, methods, and results of diabetes screening in routine clinical practice. RESEARCH DESIGN AND METHODS We studied opportunistic screening in nondiabetic members of a health maintenance or...

Abbreviations: BMI, body mass index; BP, blood pressure; DECODA, Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Asia; DECODE, Diabetes Epidemiology: Collaborative analysis Of Diagnostic criteria in Europe; DM, diabetes mellitus; FPG, fasting plasma glucose; IFG, impaired fasting glucose; IGT, impaired glucose tolerance; OGTT, oral glucose tolerance test; ROC, receiver o...