β-glucans have been reported to function as a potent adjuvant to stimulate innate and adaptive immune responses. However, β-glucans from different sources are differential in their structure, conformation, and thus biologic activity. Different preparations of β-glucans, soluble versus particulate, further complicate their mechanism of action. Here we show that yeast-derived particulate β-glucan...

Oat β-Glucans were studied for their immunological impact before and after enzymatic digestion in order to enhance the efficacy of oat β-Glucans for application in functional foods. Oat β-Glucan is reported to have minimal impact compared to its fungal counterpart in vitro. Digestion with endo-glucanase enhanced its efficacy towards stimulating MCP-1, RANTES, IL-8, and IL-4 production in human ...

Currently, the majority of prebiotics in the market are derived from non-digestible oligosaccharides. Very few studies have focused on non-digestible long chain complex polysaccharides in relation to their potential as novel prebiotics. Cereals β-glucans have been investigated for immune-modulating properties and beneficial effects on obesity, cardiovascular diseases, diabetes, and cholesterol ...

Dectin-1/CLEC7A is a pattern recognition receptor that recognizes β-1,3 glucans, and its stimulation initiates signaling events characterized by the production of inflammatory cytokines from human dendritic cells (DCs) required for antifungal immunity. β-glucans differ greatly in size, structure, and ability to activate effector immune responses from DC; as such, small particulate β-glucans are...

PURPOSE OF REVIEW To examine the recent scientific literature on the immune modulating effects of β-glucans and subsequent benefits on infection and cancer. RECENT FINDINGS β-Glucans have been investigated for their ability to protect against infection and cancer and more recently for their therapeutic potential when combined with cancer therapy. Their immune modulating effects are attributed...

Abstract Marine microalgae are a promising sustainable source of lipids, omega-3 fatty acids, and carbohydrates. Selected species belonging to the Bacillariophyceae, Haptophyceae, Eustigmatophyceae, Prasinophyceae were characterised for cellular content carbon nitrogen, production yields total carbohydrates, ?-glucans. Carbon nitrogen showed hyperbolic decrease with increasing cell numbers Chae...

Poultry as an industry was continuously growing worldwide and demands for poultry meats were markedly increasing. However, the limited use of antibiotics treatments growth promoters became a serious problem due to emergence antibiotic resistance. Therefore, exploring other alternatives such using feed additives like beta-glucans widely studied used meet consumers. This review focused on differe...

Yeast (Saccharomyces cerevisae) β-1,3 glucans were used as adjuvant in a Vibrio damsela vaccine for turbot (Scophthalmus maximus L.). Turbot were injected with the adjuvant prior, at the same time and after the vaccine. Several immune parameters (index and rate of phagocytosis, passive haemolytic plaque numbers, and agglutinating antibody titers) were determined at different times postinoculati...

β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that β-(1→3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They constitute prevalent sources of carbons for microorganisms after subsequent recognition by digesting e...