The electron microscopic appearances of the corneoscleral and iris tissue removed at operation from a child with Hurler disease and glaucoma showed distinctive swollen cells with intracellular inclusions similar to those which are observed in other tissues in these patients and which are due to abnormal lysosomal storages of mucopolysaccharides. Some recent observations on the possible relation...

PURPOSE To report a case of Propionibacterium acnes endophthalmitis in a patient with an Ahmed glaucoma valve. CASE REPORT A nine-year-old boy with bilateral congenital glaucoma, with an Ahmed glaucoma valve implanted in the left eye, had recurrent conjunctival dehiscence and endophthalmitis. RESULTS Vitreous cultures demonstrated the presence of Propionibacterium acnes. CONCLUSIONS This ...

OBJECTIVE To describe surgical strategies in a series of patients with diplopia following implantation of a glaucoma drainage device. METHODS Retrospective review of 9 consecutive patients who underwent strabismus surgery because of strabismus and diplopia after implantation of a glaucoma drainage device. RESULTS Seven patients with marked limitation to ocular rotations and incomitant strab...

Polymorphisms in the CAV1/2 genes that encode signature proteins of caveolae are associated with glaucoma, the second leading cause of blindness worldwide, and with its major risk factor, intraocular pressure (IOP). We hypothesized that caveolin-1 (Cav-1) participates in IOP maintenance via modulation of aqueous humor drainage from the eye. We localize caveolae proteins to human and murine conv...

RATIONALE Vacuum sealing drainage (VSD) is widely utilized for treating traumatic wounds. PATIENT CONCERNS It is particularly difficult and time consuming to use in combination with an external fixator. DIAGNOSES This is because the hardware or pins used for fixation interfere with maintaining a seal, resulting in poor adhesion and subsequent air leakage. INTERVENTIONS To resolve this pro...

Posterior pupillary synechiae affect a proportion of eyes subjected to iridectomy with or without drainage operation because (1) aqueous humour bypasses the pupil; (2) traumatic iridocyclitis occurs; (3) there is immobility of the iris in the iridectomy sector; (4) in eyes with angle closure glaucoma closer apposition of the iris to the anterior lens capsule increases the tendency; (5) pilocarp...

Purpose This reports a case using fibrin glue to secure a glaucoma drainage device plate to the sclera where there is a concern with the use of suture. Observations A 13-year-old patient with congenital aniridia and associated glaucoma refractory to topical medications underwent implantation of a glaucoma drainage device (GDD) for improved intraocular pressure (IOP) control. The patient had s...

The definition of glaucoma is an elevated intraocular pressure. Normal intraocular pressures in dogs are 12-24mmHg. The pressure is best measured by tonometry and the most common tonometers are the Tonopen, TonoVet, and Schiotz tonometers. The Tonopen and TonoVet are more easily utilized but the Schiotz can also be accurate when the user is adequately trained in its use. Glaucoma can be either ...