Giant cell glioblastoma is an extremely rare variant of Glioblastoma (WHO grade IV) which is characterized by a predominance of bizarre, multinucleated giant cells. These tumors comprise of 0.8% of brain tumors and up to 5% of glioblastomas. In pediatric age group, these tumors are still uncommon with only around 53 published cases since 1952. Here, we report a case of a 12-year old female pat...

Giant-cell tumor of bone is a rare, locally aggressive tumor that typically occurs in the bones of skeletally mature young adults in their second to fourth decades. Traditionally, surgery has been the mainstay of therapy for this disease, but the disease can recur even with optimal procedures. Furthermore, it may occur in locations where a surgical approach would be morbid. The maturation of th...

Giant cell tumor is a benign primary bone tumor. The phalangeal localization rare. It distinguished from other locations by the local aggressiveness of and high rate recurrence. We report one case 25-year-old right-handed nurse with no reported pathological history who complained about an ulcero-budding mass right little finger evolving year ago. She would have initially consulted bonesetter ta...

Giant cell tumor (GCT) of bone is a benign but locally aggressive and destructive lesion generally occurring in skeletally mature individuals. Typically involving the epiphysiometaphyseal region of long bones, the most common sites include the distal femur, proximal tibia and distal radius. On radiographs, GCT demonstrates a lytic lesion centered in the epiphysis but involving the metaphysis an...

Giant cell tumors is a primary benign bone tumors but with a tendency for significant local bone destruction, recurrence, and occasionally, distant metastasis. Most metastases are to the lungs but rarely metastases to the regional lymph nodes, the scalp, and the pelvis have been reported. Giant cell tumor in the elderly are very rare; and to the best of our knowledge, there is no prior report o...

Giant cell tumor of soft tissue is a rare tumor first described by Salm and Sissons in 1972 as being a distinct entity.(1) Histologically, it is composed of multinucleated giant cells dispersed among mononuclear cells, and is indistinguishable from its bone equivalent.(2) The majority of these tumors have been reported to occur in the lower extremity.(2,3) We describe a case of giant cell tumor...