Carcinomas of the lung with benign osteoclast-like giant cells are rare. A literature search showed only 8 previously reported examples. These tumors resemble a giant cell tumor of bone. Many of these tumors, which occur in most epithelium-containing organs, are composed of an undifferentiated, sarcomatoid component that contains benign osteoclast-like giant cells and a conventional carcinoma. ...

Giant cell tumor of soft parts (GCtSP) is an extremely rare soft tissue tumor that resembles its counterpart in bone. It is considered a soft tissue counterpart of giant cell tumor of the bone (1-3). The tumor is composed of an admixture of osteoclast-like multinucleated giant cells and mononuclear stromal cells (3,4). The lesion was first described in 1972 by Salm and Sissons and Guccion and e...

Diffuse type tenosynovial giant cell tumor (D-TGCT) is a locally aggressive benign proliferation. Knee joint the most commonly affected site. We present case report with 16 months follow up after recurrent surgery and postoperative radiotherapy.

Giant cell tumor of soft tissue originally described in 1972 in two different series by Salm and Sissons is a rare entity, which is clinically and histopathologically indistinguishable from giant cell tumor of bone. Usually involve thigh, trunk, and lower extremities but rarely involve the hands. GCT-ST is a benign tumor, which can transform into malignant form and also has potential for recurr...

Giant cell tumor (GCT) of bone is a giant-cell-rich bony lesion associated with abundant multinucleated osteoclast-type giant cells. It is a primary neoplasm of bone with characteristic clinical, radiological, and pathological features. It is an expansive and lytic lesion without periosteal reaction and prominent peripheral sclerosis. Giant cells are also seen in other diseases like giant cell ...