BACKGROUND Over the past decade the prevalence of gestational diabetes mellitus (GDM) has increased rapidly in both developed and developing countries and has become a growing health concern worldwide. A recent systematic review highlighted the paucity of data available on the prevalence and potential burden of GDM in Africa, which was emphasised by the fact that only 11 % of African countries ...

OBJECTIVE: Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes. C-Reactive Protein (CRP), an acute phase protein produced by hepatocytes, may be associated with diabetes. This study aimed to compare serum levels of CRP in women with gestational diabetes mellitus (GDM), impaired glucose tolerance test and control subjects. MATERIALS AND METHODS: In this ca...

OBJECTIVE To compare the ability of the fasting plasma glucose (FPG) level with the ability of the 2-hour oral glucose tolerance test (OGTT) to identify women with any form of glucose intolerance within the first six postpartum months. METHODS In a retrospective, observational analysis, the predictive ability of the FPG level was compared with that of the 2-hour OGTT in 275 women followed for...

BACKGROUND AND OBJECTIVE Diabetes in Pregnancy Study Group India (DIPSI) recommends 2-h Plasma glucose (PG) > or = 140 mg/dL with 75g oral glucose load to diagnose GDM, akin to WHO criteria. Recently, International Association of Diabetes in Pregnancy Study Group (IADPSG) recommends any one value of Fasting plasma glucose (FPG) > or = 92 mg/ dL, 1-h PG > or = 180 mg/dL or 2-h PG > or = 153 mg/d...

OBJECTIVE To determine the rate of adherence to postpartum glycemic testing in women with gestational diabetes mellitus (GDM) and the performance of fasting plasma glucose (FPG) versus the 75-g oral glucose tolerance test (OGTT) in detecting postpartum glucose intolerance. RESEARCH DESIGN AND METHODS The study was a retrospective cohort of 1,006 women with GDM attending a pregnancy diabetes c...

AIM Lipid profile and glycosylated hemoglobin level changes in gestational diabetes. The extent to which this alteration takes place is still not clearly documented. MATERIALS AND METHODS To add a clear answer to this question, lipid profile parameters, and glycosylated hemoglobin status were determined in patients with gestational diabetes mellitus and compared to healthy pregnant women (con...

OBJECTIVE This study examines the relationship of glucose intolerance during pregnancy to birth weight among black and white participants of the Pregnancy, Infection, and Nutrition Study. RESEARCH DESIGN AND METHODS This prospective cohort study recruited women from prenatal clinics in central North Carolina at 24-29 weeks' gestation. A 1-h 50-g glucose challenge test (GCT) and 100-g oral glu...

Glucose intolerance during pregnancy is defined as gestational diabetes mellitus (GDM). 95 women after 1 year birth were divided into GDM (n = 22), GIGT (gestational impaired glucose tolerance, n = 41) and NGT (normal, n = 32) groups. The GIGT group was subdivided into GIGT1 (abnormal blood glucose in 1 h, n = 11), GIGT2 (in 2 h, n = 18) and GIGT3 (in 3 h, n = 12) after oral glucose tolerance t...

Gestational diabetes mellitus has been associated with adverse maternal and infant outcomes, including preeclampsia and fetal macrosomia. Although cigarette smoking has been associated with increased insulin resistance, its effect on gestational diabetes mellitus risk is uncertain. The authors evaluated the effects of smoking on glucose tolerance in a cohort of pregnant women who participated i...