In this paper, the generalized exponential power (GEP) density is proposed as an importance function in Monte Carlo simulations in the context of estimation of posterior moments of a location parameter. This density is divided in five classes according to its tail behaviour which may be exponential, polynomial or logarithmic. The notion of p-credence is also defined to characterize and to order...

Gene expression profiling (GEP) had divided the diffuse large B-cell lymphoma (DLBCL) into molecular subgroups: germinal center B-cell like (GCB), activated B-cell like (ABC), and unclassified (UC) subtype. However, this classification with prognostic significance was not applied into clinical practice since there were more than 1000 genes to detect and interpreting was difficult. To classify c...

OBJECTIVE Amine precursor uptake and decarboxylation is a classical feature of gastroenteropancreatic (GEP) neuroendocrine tumors (NET). Production of catecholamines was studied in GEP NET and non-NET patients. DESIGN A cross-sectional study was undertaken. METHODS We studied catecholamine and metabolite secretion in 115 consecutive GEP NET patients and in 20 patients with non-NET. After sp...

Because of the limited environmental monitoring stations, the spatial data we have obtained by monitoring is local, discrete and limited. Therefore, speculating the environmental pollution parameters without monitoring station by using known monitoring data for spatial interpolation has become a hot research topic. In our preliminary work, an approach combining Genetic Expression Programming (G...

INTRODUCTION Gastroenteropancreatic (GEP) and bronchopulmonary (BP) neurendocrine neoplasms (NENs) are rare and slowly growing tumours. Matrix metalloproteinases (MMPs) degrade extracellular matrix and are responsible for invasion and metastasis. Tissue inhibitors of matrix metalloproteinases (TIMPs) affect the invasiveness of tumour cells and the formation of distant metastases. The aim of thi...

BACKGROUND Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a heterogeneous group of rare tumors. Many issues in terms of epidemiologic features, pathogenesis, and treatment of GEP-NENs are still under discussion. Our study aimed to analyze the clinicopathologic characteristics and prognosis of Chinese patients with GEP-NENs. METHODS Complete clinicopathologic data and survival ...

BACKGROUND Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are the most common type of neuroendocrine tumors, accounting for more than half of neuroendocrine neoplasms (NENs). We performed a retrospective study in our center to investigate the clinicopathological features, risk factors of metastasis, and prognosis of GEP-NENs in a Chinese population. METHODS Four hundred forty pati...

BACKGROUND There is rising incidence of gastroenteropancreatic neuroendocrine tumours (GEP- NETs) in many parts of the world, but epidemiological data from Asian populations is rare. METHODS We conducted a retrospective study in a tertiary medical centre in Hong Kong, using updated diagnostic criteria. The presentation, clinical features, and disease outcome were reviewed for all patients wit...

The aim of this paper is to introduce and study a dual problem associated to a generalized equilibrium problem (GEP). We show that the solutions of (GEP) and its dual are strictly related to the saddle points of an associated Lagrangian function, and, under some suitable conditions, to the solutions of a family of parametric optimization problems and their dual problems. Our results allow us to...

PURPOSE Advances in personalized medicine have produced novel tests and treatment options for women with breast cancer. Relatively little is known about the process by which such tests are adopted into oncology practice. The objectives of the present study were to understand the experiences of medical oncologists with multigene expression profile (gep) tests, including their adoption into pract...