In a previous paper we demonstrated how the number of possible genotypic assignments consistent with the rules of Mendelian genetics and with any known phenotypes could be calculated for an arbitrary genealogy. Here, we present further results for several regular genealogies constructed according to some specified recursive formulae and for which the growth of the genotypic statespace, with inc...

HIV drug resistance testing is becoming an integral part of antiretroviral drug development and of patient management. The parameters that characterize the performance of both phenotypic and genotypic assays and the validation of this performance are essential to their proper use for these applications. Several principles and biological factors impacting drug resistance testing are summarized. ...

Abstract Acropora cervicornis and A. palmata have experienced substantial losses in coral cover throughout the Caribbean, but their hybrid ( prolifera ) appears to be increasing at some sites. The shifts relative abundance could result from hybridization with subsequent asexual fragmentation, recent increased hybridization, or a disproportionate loss parental species. Here, acroporid taxa three...

Improvements to analytical methods have made it possible for highly discriminative genotypic information to be gleaned from smaller and smaller amounts of sample material. This fact makes it practical to genotype samples or remains consisting of bone and tooth-samples that likely would not have yielded interpretable genotypic results a short time ago. In parallel, there have been improvements t...

Dairy cows may serve as asymptomatic carriers of Salmonella. The potential for herd carrier status increases with herd size, and Salmonella shedding may be triggered by stresses placed on the animals. The scope of the current study is to determine the effects lactation may have on Salmonella genotypic diversity among detected serotypes. Fecal samples were collected on two sampling dates from 60...