نتایج جستجو برای: genomic accuracy

تعداد نتایج: 448226  

2013
Jessica E. Rutkoski Jesse Poland Jean-Luc Jannink Mark E. Sorrells

Genomic selection, a breeding method that promises to accelerate rates of genetic gain, requires dense, genome-wide marker data. Genotyping-by-sequencing can generate a large number of de novo markers. However, without a reference genome, these markers are unordered and typically have a large proportion of missing data. Because marker imputation algorithms were developed for species with a refe...

Journal: :Genetics 2012
Yi Jia Jean-Luc Jannink

Genetic correlations between quantitative traits measured in many breeding programs are pervasive. These correlations indicate that measurements of one trait carry information on other traits. Current single-trait (univariate) genomic selection does not take advantage of this information. Multivariate genomic selection on multiple traits could accomplish this but has been little explored and te...

2014
Liuhong Chen Changxi Li Mehdi Sargolzaei Flavio Schenkel

The aim of this study was to evaluate the impact of genotype imputation on the performance of the GBLUP and Bayesian methods for genomic prediction. A total of 10,309 Holstein bulls were genotyped on the BovineSNP50 BeadChip (50 k). Five low density single nucleotide polymorphism (SNP) panels, containing 6,177, 2,480, 1,536, 768 and 384 SNPs, were simulated from the 50 k panel. A fraction of 0%...

Journal: :Journal of animal science 2013
S Bolormaa J E Pryce K Kemper K Savin B J Hayes W Barendse Y Zhang C M Reich B A Mason R J Bunch B E Harrison A Reverter R M Herd B Tier H-U Graser M E Goddard

The aim of this study was to assess the accuracy of genomic predictions for 19 traits including feed efficiency, growth, and carcass and meat quality traits in beef cattle. The 10,181 cattle in our study had real or imputed genotypes for 729,068 SNP although not all cattle were measured for all traits. Animals included Bos taurus, Brahman, composite, and crossbred animals. Genomic EBV (GEBV) we...

Journal: :پژوهش های علوم دامی ایران 0
داود کریمی مجتبی طهمورث پور محمد دادپسند علی اصغر اسلمی نژاد مونز ساندو لوند

the objective of this study was to evaluate the potential gain in accuracy of predictions by imputing genotypes from a low-density marker panel (6640 marker with 10 replicates) to a medium-density marker panel in a simulated population of jersey cattle using fimpute software and also to evaluate the reliability of genomic estimate of breeding values (gebv) for milk yield (h2=0.40) and fertility...

2013
Y. D. Zhang D. J. Johnston S. Bolormaa A. Reverter M.R.S. Fortes B. Tier

Genomic selection offers the opportunity to improve female fertility in the Northern Australian beef herd. However, genomic predictions for a number of female fertility traits derived solely from the small number of female fertility records collected thus far are only of modest accuracy. In this study measures of Brahman male reproduction were used jointly with the female records, increasing th...

Journal: :Journal of animal science 2014
A Vallée J A M van Arendonk H Bovenhuis

Charolais bulls are selected for their crossbreed performance when mated to Montbéliard or Holstein dams. To implement genomic prediction, one could build a reference population for each crossbred population independently. An alternative could be to combine both crossbred populations into a single reference population to increase size and accuracy of prediction. The objective of this study was ...

Journal: :Journal of animal science 2011
C Y Chen I Misztal I Aguilar A Legarra W M Muir

Phenotypic data on BW and breast meat area were available on up to 287,614 broilers. A total of 4,113 birds were genotyped for 57,636 SNP. Data were analyzed by a single-step genomic BLUP (ssGBLUP), which accounts for all phenotypic, pedigree, and genomic information. The genomic relationship matrix (G) in ssGBLUP was constructed using either equal (0.5; GEq) or current (GC) allele frequencies,...

2016
Marco Scutari Ian Mackay David Balding

The prediction of phenotypic traits using high-density genomic data has many applications such as the selection of plants and animals of commercial interest; and it is expected to play an increasing role in medical diagnostics. Statistical models used for this task are usually tested using cross-validation, which implicitly assumes that new individuals (whose phenotypes we would like to predict...

Journal: :Genetics 2008
M P L Calus T H E Meuwissen A P W de Roos R F Veerkamp

Genomic selection uses total breeding values for juvenile animals, predicted from a large number of estimated marker haplotype effects across the whole genome. In this study the accuracy of predicting breeding values is compared for four different models including a large number of markers, at different marker densities for traits with heritabilities of 50 and 10%. The models estimated the effe...

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