نتایج جستجو برای: genetic recombination

تعداد نتایج: 646787  

Journal: :Biochemical Society transactions 2006
S Myers C C A Spencer A Auton L Bottolo C Freeman P Donnelly G McVean

Using the statistical analysis of genetic variation, we have developed a high-resolution genetic map of recombination hotspots and recombination rate variation across the human genome. This map, which has a resolution several orders of magnitude greater than previous studies, identifies over 25,000 recombination hotspots and gives new insights into the distribution and determination of recombin...

Journal: :Journal of virology 2014
Adérito L Monjane Darren P Martin Francisco Lakay Brejnev M Muhire Daniel Pande Arvind Varsani Gordon Harkins Dionne N Shepherd Edward P Rybicki

Although homologous recombination can potentially provide viruses with vastly more evolutionary options than are available through mutation alone, there are considerable limits on the adaptive potential of this important evolutionary process. Primary among these is the disruption of favorable coevolved genetic interactions that can occur following the transfer of foreign genetic material into a...

2018
Maarten J Gilbert Birgitta Duim Linda van der Graaf-van Bloois Jaap A Wagenaar Aldert L Zomer

Homologous recombination is a major driver of bacterial speciation. Genetic divergence and host association are important factors influencing homologous recombination. Here, we study these factors for Campylobacter fetus, which shows a distinct intraspecific host dichotomy. Campylobacter fetus subspecies fetus (Cff) and venerealis are associated with mammals, whereas C. fetus subsp. testudinum ...

Journal: :Proceedings of the National Academy of Sciences 1984

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