In this paper, a bi-level game-theoretic model is proposed to investigate the effects of governmental financial intervention on green supply chain. This problem is formulated as a bi-level program for a green supply chain that produces various products with different environmental pollution levels. The problem is also regard uncertainties in market demand and sale price of raw materials and pro...

OBJECTIVE We aimed to investigate the influence of positive family history (FH+) of diabetes and 19 known genetic risk loci on the effectiveness of lifestyle changes and their predictive value on the incidence of type 2 diabetes in the Finnish Diabetes Prevention Study (DPS). RESEARCH DESIGN AND METHODS A total of 522 subjects with impaired glucose tolerance (IGT) were randomized into the con...

objective: previous suicide interventional studies are controversial in their results. the present study compared brief intervention and contact (bic), with treatment as usual (tau) in their influence on the repetition of suicide attempts 6-month after the index suicide attempt. methods: adults who had attempted suicide were assigned two groups randomly: 311 in the tau and 321 in the bic. the b...

Abstract Epigenetic genome engineering expands our capabilities from modifying the DNA sequence to controlling its regulation. It provides ability change epigenetic marks at defined genomic loci control gene expression without need for an intervention in genetic code. This short review touches on current approaches of editing with a focus long-term silencing.

OBJECTIVE Previous research has shown that biological (e.g., genetic, biochemical) accounts of depression--currently in ascendancy--are linked to the general public's pessimism about the syndrome's prognosis. This research examined for the first time whether people with depressive symptoms would associate biological accounts of depression with pessimism about their own prognoses and whether a p...

Th e first three h u m a n gene transfer/therapy clinical protocols are n o w underway after having been subjected to an extensive review process by the Recombinant D N A Advisory Committee ( R A C ) and its H u m a n G e n e Therapy Subcommittee. T h e "Points to Consider" document developed by the R A C established the framework for evaluating genetic intervention protocols. This review proce...

The purpose of this special issue was to provide a forum for contemporary research and thoughtful discourse about dyslexia. Scholars from several disciplines contributed articles that advance our understanding dyslexia with regard early identification, genetic neural bases, assessment, instruction intervention educators' perspectives. In article, we introduce the issue, discuss current evidence...