BACKGROUND There is a dearth of patient, preference-based cost-effectiveness analyses evaluating genetic testing for neovascular age-related macular degeneration (NVAMD). METHODS A Value-Based Medicine, 12-year, combined-eye model, cost-utility analysis evaluated genetic testing of Category 3 AMD patients at age 65 for progression to NVAMD. The benefit of genetic testing was predicated upon t...

association of genetic polymorphism in the calpastatin (cast) gene with average daily gain was examined in iranian purebred kurdi sheep. the genotypes for cast were determined by the pcr-sscp method. blood samples were collected from 84 purebred kurdi sheep belonging to the kurdi breeding station located in the khorasan province, north-east of iran. extraction of genomic dna was based on the gu...

introduction lamb production is the largest part of income in sheep industry. therefore, the mortality rate of lambs is a key factor in profit of the sheep breeding. mortality rate of lambs (or lamb mortality rate) in different breeds of sheep under different climatic conditions is varying from 15% to 50% and an average of 9% to 20% has been reported. survival rate is a combination trait that i...

The long-term performance of different selection strategies was evaluated via simulation using the example of a local cattle breed, German Angler cattle. Different optimum contribution selection (OCS) approaches to maximize genetic gain were compared to a reference scenario without selection and truncation selection. The kinships and migrant contribution (MC) were estimated from genomic data. T...